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COVID-19 prevention measures

For every complex problem there is an answer that is clear, simple, and wrong. ~H L Menken
For the latest list of snake oil type of recommendations and cures see The Coronavirus Collection Prevention and Treatments - Snopes.com

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There are half-dozen elementary measures that would lower your risk.  You might wish to watch WHO presentation Q&A on Coronavirus - COVID-19 with WHO's Dr Maria Van Kerkhove - YouTube

But the main factor -- your age and the state of your health can't be changed. And state of your immune system -- the main barrier for the virus can't be changed too.  Also spending more time on fresh air and under direct sun exposure might improve it a little bit.

Please avoid quackery and snake oil salesmen which now are propagating via Internet, especially Facebook. See A Doctor's Tips for Spotting Fake COVID-19 News

A good news is that judging from Diamond Princess cruise ship experience less then 20% of people are susceptible to the virus even if they are over 50.  For everybody else the immune system simply kills the virus and the person never becomes infected. Also a large number of people who are tested positive never develop any symptoms and might be false positives of the test. 

Like with everything luck depends on your lack.: contact with infected person often lead to infection. Especially in public transport where people are very close to each other.

Below are somewhat reworded CDC recommendations

Stop touching your face, especially eyes and nose!

The CDC also recommends that you avoid touching your face — specifically, your eyes, nose, and mouth, which are entry portals for coronavirus and other germs. If an infected person coughs or sneezes on a surface, and you touch that contaminated surface and then touch your facial mucous membranes — the eyes, nose, and mouth — you could become infected.

Wash your hands.

Washing your hands regularly is the best way to protect yourself from coronavirus — assuming you’re doing it correctly. The CDC recommends getting your hands wet with warm or cold water; lathering your entire hands, including under the nails, with soap; scrubbing your hands for 20 seconds; rinsing with clean water; and finally, either letting your hands air-dry or using a clean towel.

“Wash them especially well if you’re about to eat,” Aaron E. Carroll, a professor of pediatrics at Indiana University School of Medicine, wrote in the New York Times. “Wash them after you’ve blown your nose, coughed or sneezed. Make it routine that all members of the household wash their hands when they get home.”

It’s also not a bad idea to carry around a hand sanitizer for times when you’re not near a sink, though you should make sure it contains at least 60 percent alcohol. However, experts stress that washing your hands thoroughly — and frequently — is the best preventative measure.

If you have a chronic illness, are elderly, or have a compromised immune system …

While COVID-19 will cause mild symptoms in the majority of infected people, Jan Carette, associate professor at the Department of Microbiology and Immunology at Stanford University’s School of Medicine, says that the elderly — especially those with chronic conditions, like hypertension or diabetes — are at greater risk for more severe disease. In this case, he recommends that those who are especially susceptible practice the above precautions as well as avoid people who display flulike symptoms.

If you’re traveling …

If you have upcoming travel plans, it’s a good idea to stay up-to-date on the CDC’s travel warnings for specific countries. In general, it’s safest to avoid nonessential travel to countries with a sustained COVID-19 presence; right now, this includes Iran, China, South Korea, and Italy. For individuals who are especially susceptible to viral infections, including the elderly and those with existing medical conditions, the CDC advises avoiding travel to Japan as well.

Currently, the CDC doesn’t have any additional recommendations for domestic travel, though this could change as the virus spreads further in the United States. But according to the CDC’s website, the risk of infection on an airplane is low. “Because of how air circulates and is filtered on airplanes, most viruses and other germs do not spread easily,” they write. However, they recommend that travelers wash their hands frequently and avoid contact with sick passengers.


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[Mar 28, 2020] Beware padding unproven advertising of Chloroquine and Hydroxychloroquione as cures for COVID-19 from Esxobar and similar unqualified folk

Mar 28, 2020 | www.unz.com

KA , says: Show Comment March 27, 2020 at 3:03 pm GMT

Hydroxyxhloroquine is antimalarial,works on the DNA , and accumulates in white blood cells . Corona virus is RNA. Possible other mechanism includes suppression of T lymphocytes , decreased white blood cell migration to the injured area ,stabilization of lysosomal enzymes which means the enzymes that can attack pathogen and also human normal cells are being prevented from release from inside the immune cells and suppression of DNA and RNA synthesis.

I am not aware that has ever been to be effective against any virus in the past. It doesn't work on the Angiotensin receptor or signal transduction down stream .

Chloroquine and Hydroxychloroquione are used for Rheumatoid arthritis but they don't alter the bone damages They are not very effective DMARDs ( disease modifying anti rheumatic drugs ) .It is also used against Graft versus Host rejection . Not effective enough.

Any antiviral medicine has to work on one of these sites or on combination of these sites- attachment of virus to cells, f penetration ( nucleus) , uncoating, protien synthesis , nucleic acid synthesis, packaging , and assembly of new virus , then the last part -viral release from cell to attack new cells. Hydroxychloroquine is not known to attack any of these processes .

Chloroquine and Hydroxychloroquine are known to work differently in rheumatoid and graft vs host disease or in some patients with SLE.

I am not sure if these 2 can be considered as an orphan drug and approved by FDA

I am not sure how French jumped to the idea that this medication would work ( usually a possible mechanism of action or anecdotal data have to be furnished before trying or have two have animal data )

So let's not celebrate French microbiologist or IHU and jump to some theories on the behaviors of French ministers or pharmaceuticals.

JT , says: Website Show Comment March 26, 2020 at 10:55 pm GMT
Since March 17th the pin on my twitter profile promotes the preventive use of chloroquine to treat the Novel Coronovirus. I've been following the debate about this anti-malarial (polio and yellow fever) drug closely. I like Escobar's article, but there are several problems with it, that even I, as a proponent of chloroquine cannot ignore.

First, the claim that Agnes Buzyn (mispelled twice in the article as "Buzy"), classified the drug as a poison, thus requiring prescription.

this is false. Chloroquine, in its market French form known as Nivaquine, was never over the counter. Never. In fact very few Western countries ever sold it over the counter. In most US states, it was prescription based. It is lethal when used inappropriately.

Second, with all due respect to Dr. Raoult, he is absolutely wrong about viral load in terminal stages of Covid-19. Corona virus is anything but low or nearly absent. In fact, its viral load is extremely high and a good measure of patient outcome at admission, and no amount of antiviral treatment can reduce it on its own at this point. Raoult was either trying to say that corona is not the cause of mortality, which is technically true, or like 99% of doctors fighting Corona, has no grasp of what the virus actually does.

The gist of the Escobar article is problematic. Nothing concrete about how Sanofi or Big Pharma is planning on cashing in by delaying chloroquine production. Last week Sanofi donated 300,000 "dosses" of chloroquine to the United States. The drug has been around for 60 years and is listed by the WHO as a required drug in all medical systems with required possibilities of local production. The criteria of which are known only to experts.

As for the theory that chloroquine supplies have been pilfered my French sources told me supplies had been seized. Macron may be pursuing a policy of herd immunity, but doesn't have the political luxury of being public about it, and a little less literalism is a helpful corrective for wild speculation. Herd immunity strategies cannot be pursued openly, being political (reelection) liabilities.

Far far more important to the coronovirus debate is how one is supposed to cure with vaccines, if the jury is still out on acquired immunity. One cannot work without the other, suggesting that the MSM acceptance of possible vaccine treatment ipso facto means acquired immunity is a given, but that's not the way the MSM and governments are presenting this, suggesting that either vaccines cannot possibly work, or that immunity is being aquired as we speak, while the facade of a fight is kept up.

utu , says: Show Comment March 27, 2020 at 4:24 am GMT
@The Obscurantist Coronavirus : Agnès Buzyn a-t-elle interdit la vente libre de chloroquine en pleine épidémie
https://www.lemonde.fr/les-decodeurs/article/2020/03/25/agnes-buzyn-a-t-elle-interdit-la-vente-libre-de-chloroquine-en-pleine-epidemie-de-covid-19_6034372_4355770.html

Since this decree, the hydroxychloroquine molecule marketed under the name of Plaquenil is therefore no longer available over the counter. A prescription from a doctor is now mandatory. But this new classification, which came into effect in January, contrary to what some conspiratorial publications suggest, predates the appearance of the new coronavirus. Its cousin, chloroquine, appears on this list "in injectable and oral form", since a decree taken in 1999.

As LCI explains, the National Health Security Agency (ANSES) had been asked for an opinion on a proposal for an order to include hydroxychloroquine in List II of poisonous substances in October 2019, "in order to ensure appropriate patient care ". Two months before the appearance of the new coronavirus in China.
ANSES had given the green light on November 12, 2019. It is therefore false and dishonest to claim that the former Minister of Health, Ms. Buzyn, would have made this decision herself during the Covid-19 epidemic.

CCZ , says: Show Comment March 27, 2020 at 2:37 pm GMT
@onebornfree The Quinism Foundation is a nonprofit charitable organization established to support education and research on chronic quinoline encephalopathy and other medical conditions caused by poisoning, or intoxication, by mefloquine, tafenoquine, chloroquine, and related quinoline drugs.

Executive Director Dr. Remington Dr. Nevin noted his concern that members of the public may even attempt to obtain therapeutic quantities of quinine through questionable channels. "Tonic water, whose bitter taste is produced by the addition of quinine or related naturally-occurring quinolines, is limited by U.S. Food and Drug Administration regulations to 83 mg per liter of quinine and related cinchona alkaloids," said Dr. Nevin. "However, drinking several bottles of tonic water will result in consuming pharmaceutical quantities, and therefore potentially harmful, amounts of these drugs", said Dr. Nevin. "Tonic water is a prescription medication masquerading as a cocktail mixer."

oneworld , says: Show Comment March 27, 2020 at 11:44 am GMT
A single, non-randomized observational trial is close to the bottom of the list in terms of meaningful medical research, down there with anecdotal reports, particularly in a novel viral disease with highly variable clinical manifestations and outcomes.

There are also significant potential cardiac risks caused by the Q-T lengthening on one's EKG caused by both azithromycin and chloroquine. Don't grasp at straws.

Turk 152 , says: Show Comment March 27, 2020 at 9:05 pm GMT
@KA You seem quite a knowledge so I hope to obtain your insights, I am not medical.

I heard that the likelihood of ARDS (cytokine storm?) can be detected by a Serum Ferritin test. If it levels are high, the patient should be given Anakinra, the rheumatoid arthritis medication, which will prevent ARDS. Neither the test, nor the treatment are being given because the average Doc who does not specialize in this field, does not know to test for this.

I understand that Hydroxychloroquin will reduce virulent symptoms in high risk patients but should be given cautiously.

Toubib Thawr , says: Show Comment March 27, 2020 at 10:06 pm GMT
KA,
I am commenting here first time but have been reading the site for years.
I have two decades of biotech research experience.
I just finished a literature survey about effects of these active pharmaceutical ingredients or APIs (chloroquine, hydroxychloroquine, hydroxychloroquine phosphate).
The APIs have been in human application for very long time and their side effect profile might be broad but it is not widespread. The most serious problems arise from eventual eye degenerative effects but those are very-very rare.
These APIs do act on several steps of what you mentioned, starting with receptor binding interference (ACE2 glycosylation changes), viral entry (impairment of endosome formation), then viral DNA offloading (interference with virus-containing endosomes fusing with lysosomes), through viral "work" (impairment of protein synthesis and virion assembly through stopping of Golgi- and endoplasmatic reticular budding and traffic).
The most interesting part of their actions might however be the inhibition of the viral RNA-dependent RNA polymerase enzyme. This is done through increasing Zn++ concentration in the cytoplasm because all of these APIs are ionophores and bring Zn++ ions into the cytosol through the lipid membrane. High Zn++ "levels" inside the cell block the "xerox machine"of the viral RNA. So indeed these have at least theoretical effects and in vitro proof is abundant.

On the contrary, if one looks at the now not too worthwile treatment compilation from Alipay and Zhezhiang University the use of different antiviral drugs is quite dangerous to the liver. Many patients on anti-retrovirals developed liver problems. I think the Shanghai Protocol is much more adequate but to each his own.

With regards to the origins of the virus someone earlier wrote about haplotypes. There are 58 haplotypes (called as such in peer-reviewed publications) and 5 haplogroups of the virus in two clades (L and S). According to a non peer-reviewed publication at ChinaXiv, 5 haplogroups have only been reported from the US so far. Mainland Chinese enjoyed the society of only 4 haplogroups while the fifth could be found in Taiwan.

Felix Keverich , says: Show Comment March 27, 2020 at 10:44 pm GMT
For your information, Russia will now be using chloroquine and hydroxychloroquine for treatment of COVID-19 in moderate to severe cases.

https://static-3.rosminzdrav.ru/system/attachments/attaches/000/049/877/original/COVID19

[Mar 28, 2020] Handbook on COVI-19 treatment put out by Chinese doctors.

Mar 28, 2020 | www.moonofalabama.org

Peter AU1 , Mar 27 2020 21:35 utc | 47

Handbook put out by Chinese doctors.
alibabacloud.com/universal-service/pdf_reader

[Mar 28, 2020] Awareness of the risk of chloroquine phosphate causing acute poisoning or even death should be strengthened

Mar 28, 2020 | www.moonofalabama.org

Likklemore , Mar 27 2020 21:18 utc | 44

@ mpn 8

Here is one published Abstract, specific to COVID-19 warns of the toxicity.

Department of Forensic Medicine, Tongji Medical College, Huanzhong University of Science and Technology, Wuhan 430030, China. LINK

The Trial of Chloroquine in the Treatment of Corona Virus Disease 2019 (COVID-19) and Its Research Progress in Forensic Toxicology.

[.]Since December 2019, COVID-19 (corona virus disease 2019) outbreaks caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has occurred in China and many countries around the world. Due to the lack of drugs against COVID-19, the disease spreads rapidly and the mortality rate is relatively high. Therefore, specific drugs against SARS-CoV-2 need to be quickly screened. The antimalarial drug Chloroquine phosphate which has already been approved is confirmed to have an anti-SARS-CoV-2 effect and has been included in diagnostic and therapeutic guidelines. However, awareness of the risk of chloroquine phosphate causing acute poisoning or even death should be strengthened. The dosage used according to current clinical recommended dosage and course of treatment are larger than that of previous treatment of malaria. Many provinces have required close clinical monitoring of adverse reactions. This paper reviews the pharmacological effects, poisoning;[.]

Peter AU1 , Mar 27 2020 22:02 utc | 53

This is the antiviral treatment recommended in the hand I linked above.
Antiviral Treatment
At FAHZU, lopinavir/ritonavir (2 capsules, po q12h) combined with arbidol (200 mg po q12h) were applied as the basic regimen. From the treatment experience of 49 patients in our hospital, the average time to achieve negative viral nucleic acid test for the first time was 12 days (95% CI: 8-15 days). The duration of negative nucleic acid test result (negative for more than 2 times consecutively with interval ≥ 24h) was 13.5 days (95% CI: 9.5 - 17.5 days).If the basic regimen is not effective, chloroquine phosphate can be used on adults between 18-65 years old (weight ≥ 50 kg: 500 mg bid; weight ≤50 kg: 500 mg bid for first two days, 500 mg qd for following five days).Interferon nebulization is recommended in Protocols for Diagnosis and Treatment of COVID-19. We recommend that it should be performed in negative-pressure wards rather than general wards due to the possibility of aerosol transmission.Darunavir/cobicistat has some degree of antiviral activity in viral suppression test in vitro, based on the treatment experience of AIDS patients, and the adverse events are relatively mild. For patients who are intolerant to lopinavir/ritonavir, darunavir/ cobici-stat (1 tablet qd) or favipiravir (starting dose of 1600 mg followed by 600 mg tid) is an alternative option after the ethical review. Simultaneous use of three or more antiviral drugs is not recommended.

Course of Treatment
The treatment course of chloroquine phosphate should be no more than 7 days. The treatment course of other regimens has not been determined and are usually around 2 weeks. Antiviral drugs should be stopped if nucleic acid test results from sputum specimens remain negative for more than 3 times

[Mar 27, 2020] High quality Microfilter bags for vacuum cleaners as apoor man mask

Mar 27, 2020 | www.moonofalabama.org

aleksandar , Mar 26 2020 20:00 utc | 26

@uncle tungsten
High quality Microfilter bags for vacuum cleaners are ways better
And you can wash them
Take care

[Mar 27, 2020] The masks are useful even if they aren't 100% useful in blocking water droplets, insofar as wearing a mask makes it much less likely that you will touch your mouth with your hands or stick your finger in your nose.

Mar 27, 2020 | www.moonofalabama.org

Yeah, Right , Mar 26 2020 21:31 utc | 57

The masks are useful even if they aren't 100% useful in blocking water droplets, insofar as wearing a mask makes it much less likely that you will touch your mouth with your hands or stick your finger in your nose.

If you also get into the habit of vigorously washing your hands before and after eating, well, you have done most of the hard yards in avoiding infection.

[Mar 27, 2020] Some important details on the France ibuprofen warning

Mar 27, 2020 | www.moonofalabama.org

c1ue , Mar 27 2020 12:36 utc | 189

Some important details on the France ibuprofen yes or no debate:
Source
The trouble over ibuprofen began March 11, when researchers at University Hospital Basel, in Switzerland, and Aristotle University of Thessaloniki, in Greece, published a letter in The Lancet Respiratory Medicine. The letter reviewed three early sets of case reports from China, covering almost 1,300 patients gravely ill with Covid-19. The letter's authors observed that significant numbers of those patients had high blood pressure and diabetes, from 12 percent to 30 percent depending on the study, and theorized that higher rates of expression of a particular enzyme, known for short as ACE2, might be raising the risk of coronavirus infection.

ACE2 provides a place on cell surfaces for the coronavirus to attach and enter in order to replicate. High blood pressure and diabetes are treated with drugs that suppress inflammation, called ACE inhibitors; the inhibitors, paradoxically, cause ACE2 to rise. That interaction is where the authors spotted a possible connection between patients experiencing chronic diseases and then becoming infected with Covid-19.

And that's where ibuprofen entered the unfolding story, too. The over-the-counter drug doesn't only knock down fever. It also reduces inflammation (the class of drugs it belongs to are known as NSAIDs, non-steroidal anti-inflammatory drugs). That effect, as with the anti-inflammatory drugs given to chronic disease patients, can cause ACE2 to rise.

So any anti-inflammatory - whether ibuprofen or actual anti-inflammatory drugs - *can* (not will) cause ACE2 to rise. And ACE2 is what nCOV latches on to.

So the acetominophen/paracetamol vs. ibuprofen has nothing to do with the fever reduction side but the potential increase of ACE2, which *might* increase susceptibility to nCOV.

[Mar 27, 2020] Do not steam your masks. they are made of polyester and will shrink into a blob

Steam can be used for decontamination of cotton, but not polister
You can spay them with alcohol
Mar 27, 2020 | www.moonofalabama.org
Passer by , Mar 26 2020 19:04 utc | 7
On the protection issue, use FFP 3 respirator masks (EU), or N99 (US) or KN 99 (China) and scarf over it. These masks filter 98 % of micro particles, including viruses. In case of mask shortages steam can be used to decontaminate masks. Also use gloves, eye protection and raincoat when in risky areas. Everything new taken in your home must be under 3 - 4 days quarantine in separate room. The raincoat too. After this quarantine items can be further cleaned with steam, ethanol, bleach + water, and groceries via soap and water.

Virus can stay for 3 hours in mid air (room) and 3 days on some surfaces. And it is possible that can even survive for up to 17 days on some surfaces, which would be pretty bad news. At least 5 meters distance between people outside is needed.

A.L. , Mar 26 2020 19:57 utc | 24

PSA:

1. do not steam your masks. they are made of polyester and will shrink into a blob. people have tried and failed. you can wash with soap and dry or low temp bake as B suggested. they will eventually fail from delaminating or the elastic band snapping.

2. stop behaving like you don't want to catch it, behave like you have it and you don't want others to catch it. we'll all be better off.

3. going on 2 - wearing masks with exhaust valves will just spray virus straight out of you're infected. if you're not sure you're infected (and you don't) wearing a valves N95 is just a dick act.

4. when PPE were in short supply in China, what they did was to wear N95 with surgical mask over the top. it's definitely off-label use but at least you can then reuse your precious N95 as it's shielded from external pathogens, at the same time your own exhaust valve (see 3) is also shielded from others.

[Mar 27, 2020] Malaria vs. coronavirus

Mar 27, 2020 | www.moonofalabama.org

Peter AU1 , Mar 27 2020 11:53 utc | 184

Malaria is a single cell bug called a protozoa. My understanding that is a class of bugs like bacteria and viruses are classes of bugs.

Mosquitoes carry or host the bug and pass it onto people. The quinine type drugs block the bug and prevent it from attaching or entering cells. That is how the drug also works against the corona viruses. Various strains of the malaria bug have developed resistance to various drugs.

Because SARS-CoV-2 is a new bug, it should not have developed a resistance to any drug.

Human immunity is directed at pathogens and seems very specific even to strains as can be seen with influenza vaccines, and the malaria protozoa is a very different animal to the SARS-CoV-2 virus.

That's the basics as I know it. Others here may be able to explain it a little better.

[Mar 27, 2020] This is an hour with experts who ran the Singapore response

Mar 27, 2020 | www.moonofalabama.org

jayvee , Mar 27 2020 1:53 utc | 110

This is an hour with experts who ran the Singapore response. It answers many of our questions and also those which cannot yet be answered. I resisted listening because it's an hour, but it was worthwhile.
https://www.youtube.com/watch?v=b3w8gu9S3lo

[Mar 27, 2020] We must also introduce the wearing of a mask in public as a new social norm:

Mar 27, 2020 | www.moonofalabama.org

MoA - More Bits On The Corona Crisis

Tests and care for Covid-19 must be for free. We need hospitals to care for only the critical cases. We need quarantine centers to isolate the milder cases from the wider population. Many hotels, sport arenas and exhibition halls are currently empty. They can be converted into quarantine stations within a day or two. People will have to stay for only two weeks. They would be fed and would have medical attention. That is a small restriction of the freedom of a few for a large benefit for our societies.

We must also introduce the wearing of a mask in public as a new social norm:

A number of studies have reported that a significant portion of people are even spreading the virus while presymptomatic -- in the day or two before they start to feel ill. Presymptomatic spreaders are, well, gonna spread. It's not their fault.

How much this type of transmission is driving the pandemic is unclear but it could be significant. Gabriel Leung, dean of medicine at the University of Hong Kong, has estimated about 40% of cases transmit before symptoms develop. A recent preprint -- a study that has not yet been peer-reviewed -- from China pooled data from seven countries and estimated a very similar 43%.

The novel coronavirus is spread to a large part by people who stay asymptomatic and by people who do not yet feel sick but will later show symptoms. When they talk, sneeze or cough they release small droplets that carry viruses. The droplets can stay in the air for some time. If a person coming along inhales those droplets the viruses will likely infect that person.

Those who have have the virus or might spread it should wear a mask because it prevents their droplets from flying out. Those who do not have the virus should wear a mask to prevent droplets from entering their body.

We were told that 'masks don't work' because they are not a 100% protection. The very tiny viruses can pass behind the mask at its sides or they can slip through its webbing. But the virus is not traveling alone but as part of a droplet. Even a relatively wide webbing may hold it up. If it is doubled with a sheet of cosmetic paper towel in between the protection will be even better. Microfilter bags for vacuum cleaners and so called HEPA filters are also effective materials that are readily available and easy to turn into masks.

The development of the epidemic will depend on how many people will start to regularly wear masks when they are not at home. Even if the protection masks prevent only 50% of new infections the speed with which the epidemic will unfold will be significantly lower.


Source: Financial Times - bigger

Consider that the societies in the blue circle are all ones where people regularly wear masks while the other countries (except China which was surprised by the outbreak) are societies were wearing a mask is seen as unusual. These 'blue' countries, which also gained experience during the SARS and MERS epidemics, show significant flatter trajectories.

Graphs similar to the above for all U.S. states and territories can be found here .

Meanwhile U.S. media continue to spread anti-China propaganda:

Two European Countries Report High Error Rate For Chinese Supplied Coronavirus Tests

Medical personnel in Spain and the Czech Republic have reported that the coronavirus rapid tests their respective countries have received from China are faulty and have a high error rate.

Several labs in Spanish hospitals have reported that the test kits they purchased, manufactured by Chinese company Bioeasy and based in Shenzhen, have a sensitivity of 30% when the sensitivity should be above 80%, Spanish newspaper El País reported Thursday. Due to the test's lack of reliability, medical personnel in Spain have switched back to the PCR test, which takes up to four hours for a diagnosis, while rapid tests take between 10 to 15 minutes

The Spanish government purchased 340,000 tests from the Chinese company, a similar quantity to the tests ordered by the Czech Republic, where medical personnel also report an 80% failure rate.

When one checks the original reports from Spain and from the Czech Republic one learns that these countries bought anti-body tests which only react when a person has had the virus for some time and developed anti-bodies against it. These tests can obviously not be used to find persons who are infected but have not yet developed anti-bodies.

China's ambassador in Spain also pointed out that these tests have yet to be verified by the regulator and were imported without the help or knowledge of the Chinese government.

The anti-body tests are valuable to identify people who have developed current immunity against the virus. These people can then care for those who are most endangered by the disease. Anti-body tests are quick. They can be used anywhere.

The polymerase chain reaction (PCR) tests which are currently necessary to find if someone has the virus take at least four hours and specialized laboratories to process them. We will need a much quicker reliable test if we want to put our economies back to work. Luckily several companies and academic groups are already working on these and a 45 minute test is now ready to be marketed .

When we have a quick test for the virus and a quick test for anti-bodies available in mass we can restart the economy by 'filtering' through the population on a large scale. Movement restrictions would then only be needed for those who show virus-positive and anti-body negative results. All others could go back to work.

There would certainly still be outbreaks from people who escaped the 'filtering' process but with easy testing and care in place those clusters can be locally contained.

It may take another two month or so to get to that point. Until then there is little we can do but to stay apart as much as possible and to wear our masks.

[Mar 27, 2020] Questions, questions, questions

Mar 27, 2020 | www.moonofalabama.org

chu teh , Mar 27 2020 3:01 utc | 120

@Richard Steven Hack | Mar 26 2020 23:39 utc | 88

re spread of CV19--yr post interests me.

Have seen no data on how many viral particles it takes to cause a serious effect. Likely, such data would be in terms of probability at X [number of viral particles]. Such is known for many infective agents in surface and aerosol form, but CV19 may be very different.

Can CV19 vapor aerosol from mouth/breath in still air, exclusive of explosive discharge via cough/sneeze, cause full-blown case beyond 6 feet? I'd like to know.

Also, have not seen any data re time duration of infective after it enters throat passage on journey to lungs. I posit that there are anti-viral liquids that might be effective if small amount were trickled down throat 2x per day; surely just before bedtime to discourage the next 7-hs of undisturbed incubation. I do take something that I am guessing may be effective. [E.g., I also
"heard" OliveOilExtract as anti-viral but I have no experience with it.]

Another thought: Re different strains of CV19 having very different outcomes...Anyone suggestion that US forms collectively having, say, milder outcomes relative to China/Iran/LombardyItaly, etc? Seems to be an aversion to testing the general population, or even publishing all results of the small amount of tests with time+place data. Where are the lists of 1st observations of "unusual flu" in US? that would NORMALLY, provoke tracking + names/places of sequential contacts?

Routine discovery and mapping of communication lines is very likely to uncover a lot of truth. That is what rational folks desire.

[Mar 26, 2020] Nearly 40% of the Italian fatalities were using ACE inhibitors (and this may be an underestimate as pre-admission medication charts were lacking). The virus binds to the pulmonary ACE2 receptor.

Mar 26, 2020 | www.unz.com

gfhÄndel , says: Show Comment March 25, 2020 at 11:48 am GMT

I will keep this comment as brief as possible.
I welcome refutation of these theses, which I believe are crucial to any analysis of the response to the pandemic:
1. Current screening tests for COVID19 (a PCR test, not an antibody test) have a high rate of false positives (see excellent contributions on this topic from Kratoklastes).
2. Draconian public health responses are allegedly aimed at minimizing serious COVID19 disease (severe respiratory distress, up to and including ARDS). "Positive" testing individuals overwhelming do not fall into this category.
3. At this juncture, our best single metric is death from COVID19. Unfortunately the definition of a COVID19 fatality varies between jurisdictions. To be counted as such a fatality, the current best definition would be: novel coronovirus IgM (+/- IgG) positive (proof of recent infection) plus ARDS (radiologically, if not pathologically, confirmed).
4. Alleged COVID19 fatalities are overwhelming patients >70 having 3 or more serious comorbidities.
5. There is an association between ACE-inhibitor or AT-receptor antagonist use and likelihood of death from infection by novel coronavirus.

To the last point: nearly 40% of the Italian fatalities were using ACE inhibitors (and this may be an underestimate as pre-admission medication charts were lacking). The virus binds to the pulmonary ACE2 receptor.
Conceivably the use of ACE-inhibitors (or the related AT-receptor antagonists) induces upregulation of this receptor, but this is purely conjecture on my part.
Anecdotally, use of this medication class is lower in Germany, which has been proffered among reasons for its lower fatality rates.

[Mar 26, 2020] An antibody test for COVID-19 virus exposure is near to becoming commercially available and this is likely to be widely used in order to identify people who can safely volunteer to help with the pandemic it may provide some interesting statistics and a different management perspective.

Mar 26, 2020 | www.unz.com

macilrae , says: Show Comment Next New Comment March 25, 2020 at 6:36 pm GMT

@Realist I have two family members in UK who have already recovered after testing positive and I, myself, suffered ten days with an unpleasant dry cough, malaise and low grade fever late in February – which has since cleared uneventfully. I was never tested and, following my GP, discounted being infected with COVID-19 at that time.

An antibody test for COVID-19 virus exposure is near to becoming commercially available and this is likely to be widely used in order to identify people who can safely volunteer to help with the pandemic – it may provide some interesting statistics and a different management perspective.

[Mar 25, 2020] Sterilization of used face masks

Probably the simplest is ironing with iron set to 200F or so
Mar 25, 2020 | www.unz.com

Saggy , says: Website Show Comment March 25, 2020 at 1:13 pm GMT

@joe webb You can google up several papers on the subject, apparently the best method is to use UV light https://www.nytimes.com/2020/03/20/health/coronavirus-masks-reuse.html
I just ordered a UV sterilization box from Amazon or Ebay (can't remember), you need to check that it's shipped from the US as most are shipped from China and take a while. The other easily available method is heat, but here it's difficult to determine the time/temp parameters https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186217

[Mar 25, 2020] Sun helps but not absolutly

Mar 25, 2020 | www.moonofalabama.org

TJ , Mar 23 2020 21:02 utc | 67

@54 Per/Norway

" The second thing that's good about it is the sun. Ultraviolet light kills viruses."

The disease is spreading in the southern hemisphere which is in summer with much higher UV just as rapidly as the northern hemisphere which is in winter with much less UV. So the data at least in this case says no. BTW she retired in 2008, and she seems to have done some impressive work in the past, though as they say in the small print of adverts for investments, past performance is no predictor of future performance.

[Mar 24, 2020] #Coronavirus - Israeli Defense Minister Gives A Speech

His main advice is to separate old people from young and wait until young people will be immune to the virus.
Mar 24, 2020 | www.youtube.com

Georgios Paraskeva , 1 day ago

'' want it or not the rest of the population is gonna get the Coronavirus''...wow !!! you are are sooo sure about it ...i bet you know thinks that we don't , probably you knew this since last year

Devrat1 , 2 days ago

Very informative .. Thank you and I agree almost totally.. only thing that I find is an error is immunity to virus. Immunity will be there with young and active people. The virus can still be transmitted. Older generation will continue to be susceptible to the virus unless we have a medicine for corona virus.

Valkyrie angel , 15 hours ago

Haha No grandma hugs grandson.. once the epidemic over grandma and grandpa come out... its way so light to express... cute..

[Mar 24, 2020] So why should people who already see a max of 5 persons a week be under house arrest? Masks are evidently a solution

Notable quotes:
"... Instead the French authorities are now trying to prepare people for work by saying that people should not go out at all because when they do they touch the left button, the doors etc. ..."
"... They can just wear gloves and clean up whatever they touch with alcohol, no? Why aren't such cheap things not distributed widely, household by household? ..."
Mar 24, 2020 | www.moonofalabama.org

Mina , Mar 24 2020 9:54 utc | 200

Another interesting feature of the shock strategy currently applied is that until planes and trains and stadiums were not plugged off, one can imagine that the virus was spreading on a much bigger scale than without these going on as usual.

So why should people who already see a max of 5 persons a week (close enough) be under house arrest? masks are evidently a solution.

Instead the French authorities are now trying to prepare people for work by saying that people should not go out at all because when they do they touch the left button, the doors etc.

But what of asking people for responsibility?

They can just wear gloves and clean up whatever they touch with alcohol, no? Why aren't such cheap things not distributed widely, household by household?

The French are doing worse because they have no community planning, unlike Belgium, the Netherlands, the UK and other northern countries. I haven't heard anyone on French media say that the municipalities or district social centres could play a role in better mapping the needs.

It seems to be entirely on the shoulders of our super-centralized gov and the hospitals! With the results we see (and we are actually doing not so bad: 5 % of the positive seem to die, vs 10% in Spain and Italy -using the figures given here

https://www.ft.com/coronavirus-latest)

[Mar 24, 2020] COVID-19 Symptoms Could Include Loss Of Smell And Taste

Mar 24, 2020 | www.youtube.com

There's growing concern among health officials about so called silent spreaders, people who are infected with the coronavirus, but aren't sick. Now some UK doctors say there may be a clue to who's carrying it and they want the loss of smell and taste added to the list of symptoms.

[Mar 24, 2020] Jack Ma placed a message on Twitter regarding availability of a Handbook related to Coronavirus for medical workers and anyone else who is interested.

Mar 24, 2020 | www.moonofalabama.org

Tom_LX , Mar 24 2020 7:01 utc | 182

Jack Ma placed a message on Twitter regarding availability of a Handbook related to Coronavirus for medical workers and anyone else who is interested.

Jack Ma Handbook

[Mar 24, 2020] NYT reports that loss of sense of smll night be an important symptom that you are infected with the corornovirus

Mar 24, 2020 | www.moonofalabama.org

blues , Mar 24 2020 4:32 utc | 165

This may be an important new clue:

~~~~~~~~~~~~~~~~~~~~ //
Lost Sense of Smell May Be Peculiar Clue to Coronavirus Infection
The New York Times - March 22, 2020

A mother who was infected with the coronavirus couldn't smell her baby's full diaper. Cooks who can usually name every spice in a restaurant dish can't smell curry or garlic, and food tastes bland. Others say they can't pick up the sweet scent of shampoo or the foul odor of kitty litter.

Anosmia, the loss of sense of smell, and ageusia, an accompanying diminished sense of taste, have emerged as peculiar telltale signs of Covid-19, the disease caused by the coronavirus, and possible markers of infection.

On Friday, British ear, nose and throat doctors, citing reports from colleagues around the world, called on adults who lose their senses of smell to isolate themselves for seven days, even if they have no other symptoms, to slow the disease's spread. The published data is limited, but doctors are concerned enough to raise warnings.
// ~~~~~~~~~~~~~~~~~~~~

[Mar 24, 2020] A woman in Chicago has developed a new function for the bra, one half of bra can serve as a mask

Mar 24, 2020 | www.youtube.com

SCODI OFFICER:001 , 4 days ago

Y'all know the chinese already did this back when SARS was around.

Ennis XU , 2 days ago

Somehow better than strawberry containers from ALDI

[Mar 24, 2020] Titillating advice

Mar 24, 2020 | www.youtube.com

A woman in Chicago has developed a new function for the bra, one that could help people escape dange - YouTube

alan king , 12 hours ago

titillating advice

[Mar 24, 2020] https://news.yahoo.com/us-orders-first-shutdown-website-over-coronavirus-fraud-023738032.html

Highly recommended!
Mar 22, 2020 | news.yahoo.com

US authorities are working to combat the spread of misinformation that has blossomed since the start of the coronavirus pandemic (AFP Photo/Alastair Pike) Washington (AFP) - The US Department of Justice announced Sunday it had shut down a website claiming to sell a coronavirus vaccine, in its first act of federal enforcement against fraud in connection with the pandemic.

Lawsuits had been filed against the site coronavirusmedicalkit.com, which claimed to sell vaccines for COVID-19, the disease caused by the novel coronavirus, when in fact there is no such vaccine, the Justice Department said in a statement.

A Texas federal judge on Saturday ordered the site to shut down, according to the statement. Its homepage, however, was still accessible as of Sunday evening.

"Due to the recent outbreak for the Coronavirus (COVID-19) the World Health Organization is giving away vaccine kits. Just pay $4.95 for shipping," read a statement on the homepage.

It was followed by a place to leave bank account information to pay shipping fees.

The Justice Department did not specify how many people fell victim to the scam, but the investigation is ongoing to identify who is behind the fraud and how much money was stolen.

The intervention by the federal judiciary system is part of ongoing efforts by US authorities to combat the spread of misinformation that has blossomed since the start of the pandemic.

Attorney General Bill Barr last week urged federal prosecutors to make stopping misinformation a priority and called US civilians to report all such abuses to the National Center for Disaster Fraud.

He also warned citizens against a variety of scams including selling fake treatments online, imitating emails from the WHO or the Centers for Disease Control and Prevention (CDC) intended to collect personal data, and asking for donations for imaginary organizations.

Simultaneously, the US judicial system is on the warpath to combat price gouging of products such as hand sanitizer or hygienic masks.

More than 33,000 people have been infected by the coronavirus in the US, and 416 have died, according to a tracker managed by Johns Hopkins University.

[Mar 24, 2020] Super-spreaders - mostly young fools ignoring social distancing on beaches, in parks, restaurants etc - are now popping up, most recently returning from Florida spring break

Mar 24, 2020 | www.moonofalabama.org

Trisha , Mar 23 2020 19:06 utc | 27

Thanks b for the update.

Unfortunately, we in the US are way behind the curve in finding and locking down clusters. In fact super-spreaders - mostly young fools ignoring social distancing on beaches, in parks, restaurants etc - are now popping up, most recently returning from Florida spring break to Utah. Testing rates remain abysmal.

Idaho cases just went exponential, doubling about every 3 days. Republic Governor there is pretty much a copy of Trump, as in a dangerous idiot, giving press conferences with multiple staff hovering around, downplaying the risks, lying about test availability, talking about protecting businesses, etc.

[Mar 23, 2020] Some inventive modern ways to disinfect masks

Microware can be used for cleaning if you make the mask slightly wet. In this case they will heat to over 60 0 C. Other then using alcohol this is probably the fastest method of disinfection
Mar 23, 2020 | www.moonofalabama.org
Don Utter , Mar 23 2020 18:11 utc | 4
Can a mask be cleaned by a microwave?

Taffyboy , Mar 23 2020 18:51 utc | 21

@4

If you can, get one of these, and there are 110 volt UVC lamps also.

https://www.amazon.ca/Germicidal-Lamp-Ozone-Light-Covers/dp/B07RWZ5SG6/ref=sr_1_10?crid=2RDBYXDA7Q4F2&keywords=uvc+lamp+germicide&qid=1584989398&sprefix=uvc+lamp%2Caps%2C913&sr=8-10

[Mar 23, 2020] Fake science: Dr. Dan Lee Dinke claims that breathing hot air in a sauna for 20 minutes will mostly clean the upper respiratory tract of corona-viruses

Sauna or hot tube might help as it raise body temperature to fever levels and as such inhibit spreading of the virus.
Mar 23, 2020 | www.moonofalabama.org
LP , Mar 22 2020 18:50 utc | 52
Sauna is your friend:

https://youtu.be/vz5KmKKiuqk

Dr. Dan Lee Dinke: All Corona-viruses have a common weakness:heat kills them. Specifically relative short exposure to 56°C. Breathing hot air in a sauna for 20 minutes will mostly clean the upper respiratory tract of corona-viruses, but a hair dryer can also help if no sauna available.

The video is worth to watch and could save lives through such a simple method.

c1ue , Mar 22 2020 19:22 utc | 57

@LP #52
Wrong. The lower respiratory tract - the temperature is stable via mixing outside air with inside. Otherwise people could not survive in extreme cold or extreme heat situations.

The hot air might kill the virus outside; it won't kill the virus in the lower respiratory tract.

[Mar 23, 2020] Perspectives of using mRNA technology for a vaccine for the COVID-19

Mar 23, 2020 | www.moonofalabama.org

Likklemore , Mar 22 2020 14:55 utc | 2

I read of the new tool scanning online messages. Checking in: late afternoon my two comments, in reply, failed to appear in the "Western Governments failures" thread.

Coronavirus, Vaccines and the Gates Foundation -
F. William Engdahl delves into the new mRNA vaccine.


[.] Gates Foundation monies via CEPI are financing development of a radical new vaccine method known as messengerRNA or mRNA.

They are co-funding the Cambridge, Massachusetts biotech company, Moderna Inc., to develop a vaccine against the Wuhan novel coronavirus, now called SARS-CoV-2. Moderna's other partner is the US National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health (NIH). Head of NIAID is Dr Anthony Fauci, the person at the center of the Trump Administration virus emergency response. Notable about the Fauci-Gates Moderna coronavirus vaccine, mRNA-1273, is that it has been rolled out in a matter of weeks, not years, and on February 24 went directly to Fauci's NIH for tests on human guinea pigs, not on mice as normal. Moderna's chief medical adviser, Tal Zaks, argued, "I don't think proving this in an animal model is on the critical path to getting this to a clinical trial."

Another notable admission by Moderna on its website is the legal disclaimer, "Special Note Regarding Forward-Looking Statements: These risks, uncertainties, and other factors include, among others: the fact that there has never been a commercial product utilizing mRNA technology approved for use." In other words, completely unproven for human health and safety.

Another biotech company working with unproven mRNA technology to develop a vaccine for the COVID-19 is a German company, CureVac. Since 2015 CureVac has received money from the Gates Foundation to develop its own mRNA technology. In January the Gates-backed CEPI granted more than $8 million to develop a mRNA vaccine for the novel coronavirus.[.]

======
early fall the CDC planning and forgot to order test kits and ventilators:---{hapstance} ---the recruitment of

Public Health Advisors (Quarantine Program) country wide major cities, every state
Open Period:2019-11-15 to 2020-05-15 Salary $511440. to $93077.
Job summary: - responsible for preventing the importation and spread of communicable diseases from abroad and spread of these diseases domestically.[.]

Duties:
[Provide technical assistance, consultation and guidance to national, state and / or local agencies; health organizations; federal, state and local law enforcement agencies [.] and quarantine activities [.] ]

[Mar 22, 2020] In 1918, anyone at the emergency hospital in Boston who had contact with patients had to wear an improvised face mask.

Mar 22, 2020 | medium.com

Face Masks Coronavirus and Flu

Surgical masks are currently in short supply in China and elsewhere. They were worn 100 years ago, during the great pandemic, to try and stop the influenza virus spreading. While surgical masks may offer some protection from infection they do not seal around the face. So they don't filter out small airborne particles. In 1918, anyone at the emergency hospital in Boston who had contact with patients had to wear an improvised face mask. This comprised five layers of gauze fitted to a wire frame which covered the nose and mouth. The frame was shaped to fit the face of the wearer and prevent the gauze filter touching the mouth and nostrils. The masks were replaced every two hours; properly sterilized and with fresh gauze put on. They were a forerunner of the N95 respirators in use in hospitals today to protect medical staff against airborne infection.

... ... ...

Putting infected patients out in the sun may have helped because it inactivates the influenza virus.[7] It also kills bacteria that cause lung and other infections in hospitals.[8] During the First World War, military surgeons routinely used sunlight to heal infected wounds.[9] They knew it was a disinfectant. What they didn't know is that one advantage of placing patients outside in the sun is they can synthesise vitamin D in their skin if sunlight is strong enough. This was not discovered until the 1920s. Low vitamin D levels are now linked to respiratory infections and may increase susceptibility to influenza.[10] Also, our body's biological rhythms appear to influence how we resist infections.[11] New research suggests they can alter our inflammatory response to the flu virus.[12] As with vitamin D, at the time of the 1918 pandemic, the important part played by sunlight in synchronizing these rhythms was not known.

[Mar 22, 2020] Coronavirus and the Sun a Lesson from the 1918 Influenza Pandemic by Richard Hobday

Notable quotes:
"... The masks were replaced every two hours; properly sterilized and with fresh gauze put on. They were a forerunner of the N95 respirators in use in hospitals today to protect medical staff against airborne infection. ..."
Mar 10, 2020 | medium.com

Fresh air, sunlight and improvised face masks seemed to work a century ago; and they might help us now.

by Richard Hobday

When new, virulent diseases emerge, such SARS and Covid-19, the race begins to find new vaccines and treatments for those affected. As the current crisis unfolds, governments are enforcing quarantine and isolation, and public gatherings are being discouraged. Health officials took the same approach 100 years ago, when influenza was spreading around the world. The results were mixed. But records from the 1918 pandemic suggest one technique for dealing with influenza -- little-known today -- was effective. Some hard-won experience from the greatest pandemic in recorded history could help us in the weeks and months ahead.

<img src="https://miro.medium.com/max/2400/1*7pNa3EQCs1VsWXRWL8_Uig.jpeg" width="1200" height="892" role="presentation"/>
Influenza patients getting sunlight at the Camp Brooks emergency open-air hospital in Boston. Medical staff were not supposed to remove their masks. (National Archives)

Put simply, medics found that severely ill flu patients nursed outdoors recovered better than those treated indoors. A combination of fresh air and sunlight seems to have prevented deaths among patients; and infections among medical staff.[1] There is scientific support for this. Research shows that outdoor air is a natural disinfectant. Fresh air can kill the flu virus and other harmful germs. Equally, sunlight is germicidal and there is now evidence it can kill the flu virus.

`Open-Air' Treatment in 1918

During the great pandemic, two of the worst places to be were military barracks and troop-ships. Overcrowding and bad ventilation put soldiers and sailors at high risk of catching influenza and the other infections that often followed it.[2,3] As with the current Covid-19 outbreak, most of the victims of so-called `Spanish flu' did not die from influenza: they died of pneumonia and other complications.

When the influenza pandemic reached the East coast of the United States in 1918, the city of Boston was particularly badly hit. So the State Guard set up an emergency hospital. They took in the worst cases among sailors on ships in Boston harbour. The hospital's medical officer had noticed the most seriously ill sailors had been in badly-ventilated spaces. So he gave them as much fresh air as possible by putting them in tents. And in good weather they were taken out of their tents and put in the sun. At this time, it was common practice to put sick soldiers outdoors. Open-air therapy, as it was known, was widely used on casualties from the Western Front. And it became the treatment of choice for another common and often deadly respiratory infection of the time; tuberculosis. Patients were put outside in their beds to breathe fresh outdoor air. Or they were nursed in cross-ventilated wards with the windows open day and night. The open-air regimen remained popular until antibiotics replaced it in the 1950s.

Doctors who had first-hand experience of open-air therapy at the hospital in Boston were convinced the regimen was effective. It was adopted elsewhere. If one report is correct, it reduced deaths among hospital patients from 40 per cent to about 13 per cent.[4] According to the Surgeon General of the Massachusetts State Guard:

`The efficacy of open air treatment has been absolutely proven, and one has only to try it to discover its value.'

Fresh Air is a Disinfectant

Patients treated outdoors were less likely to be exposed to the infectious germs that are often present in conventional hospital wards. They were breathing clean air in what must have been a largely sterile environment. We know this because, in the 1960s, Ministry of Defence scientists proved that fresh air is a natural disinfectant.[5] Something in it, which they called the Open Air Factor, is far more harmful to airborne bacteria -- and the influenza virus -- than indoor air. They couldn't identify exactly what the Open Air Factor is. But they found it was effective both at night and during the daytime.

Their research also revealed that the Open Air Factor's disinfecting powers can be preserved in enclosures -- if ventilation rates are kept high enough. Significantly, the rates they identified are the same ones that cross-ventilated hospital wards, with high ceilings and big windows, were designed for.[6] But by the time the scientists made their discoveries, antibiotic therapy had replaced open-air treatment. Since then the germicidal effects of fresh air have not featured in infection control, or hospital design. Yet harmful bacteria have become increasingly resistant to antibiotics.

Sunlight and Influenza Infection

Putting infected patients out in the sun may have helped because it inactivates the influenza virus.[7] It also kills bacteria that cause lung and other infections in hospitals.[8] During the First World War, military surgeons routinely used sunlight to heal infected wounds.[9] They knew it was a disinfectant. What they didn't know is that one advantage of placing patients outside in the sun is they can synthesise vitamin D in their skin if sunlight is strong enough. This was not discovered until the 1920s. Low vitamin D levels are now linked to respiratory infections and may increase susceptibility to influenza.[10] Also, our body's biological rhythms appear to influence how we resist infections.[11] New research suggests they can alter our inflammatory response to the flu virus.[12] As with vitamin D, at the time of the 1918 pandemic, the important part played by sunlight in synchronizing these rhythms was not known.

Face Masks Coronavirus and Flu

Surgical masks are currently in short supply in China and elsewhere. They were worn 100 years ago, during the great pandemic, to try and stop the influenza virus spreading.

While surgical masks may offer some protection from infection they do not seal around the face. So they don't filter out small airborne particles.

In 1918, anyone at the emergency hospital in Boston who had contact with patients had to wear an improvised face mask. This comprised five layers of gauze fitted to a wire frame which covered the nose and mouth. The frame was shaped to fit the face of the wearer and prevent the gauze filter touching the mouth and nostrils.

The masks were replaced every two hours; properly sterilized and with fresh gauze put on. They were a forerunner of the N95 respirators in use in hospitals today to protect medical staff against airborne infection.

Temporary Hospitals

Staff at the hospital kept up high standards of personal and environmental hygiene. No doubt this played a big part in the relatively low rates of infection and deaths reported there. The speed with which their hospital and other temporary open-air facilities were erected to cope with the surge in pneumonia patients was another factor. Today, many countries are not prepared for a severe influenza pandemic.[13] Their health services will be overwhelmed if there is one. Vaccines and antiviral drugs might help. Antibiotics may be effective for pneumonia and other complications. But much of the world's population will not have access to them. If another 1918 comes, or the Covid-19 crisis gets worse, history suggests it might be prudent to have tents and pre-fabricated wards ready to deal with large numbers of seriously ill cases. Plenty of fresh air and a little sunlight might help too.

Dr. Richard Hobday is an independent researcher working in the fields of infection control, public health and building design. He is the author of `The Healing Sun'.

References

  1. Hobday RA and Cason JW. The open-air treatment of pandemic influenza. Am J Public Health 2009;99 Suppl 2:S236–42. doi:10.2105/AJPH.2008.134627.
  2. Aligne CA. Overcrowding and mortality during the influenza pandemic of 1918. Am J Public Health 2016 Apr;106(4):642–4. doi:10.2105/AJPH.2015.303018.
  3. Summers JA, Wilson N, Baker MG, Shanks GD. Mortality risk factors for pandemic influenza on New Zealand troop ship, 1918. Emerg Infect Dis 2010 Dec;16(12):1931–7. doi:10.3201/eid1612.100429.
  4. Anon. Weapons against influenza. Am J Public Health 1918 Oct;8(10):787–8. doi: 10.2105/ajph.8.10.787.
  5. May KP, Druett HA. A micro-thread technique for studying the viability of microbes in a simulated airborne state. J Gen Micro-biol 1968;51:353e66. Doi: 10.1099/00221287–51–3–353.
  6. Hobday RA. The open-air factor and infection control. J Hosp Infect 2019;103:e23-e24 doi.org/10.1016/j.jhin.2019.04.003.
  7. Schuit M, Gardner S, Wood S et al. The influence of simulated sunlight on the inactivation of influenza virus in aerosols. J Infect Dis 2020 Jan 14;221(3):372–378. doi: 10.1093/infdis/jiz582.
  8. Hobday RA, Dancer SJ. Roles of sunlight and natural ventilation for controlling infection: historical and current perspectives. J Hosp Infect 2013;84:271–282. doi: 10.1016/j.jhin.2013.04.011.
  9. Hobday RA. Sunlight therapy and solar architecture. Med Hist 1997 Oct;41(4):455–72. doi:10.1017/s0025727300063043.
  10. Gruber-Bzura BM. Vitamin D and influenza-prevention or therapy? Int J Mol Sci 2018 Aug 16;19(8). pii: E2419. doi: 10.3390/ijms19082419.
  11. Costantini C, Renga G, Sellitto F, et al. Microbes in the era of circadian medicine. Front Cell Infect Microbiol. 2020 Feb 5;10:30. doi: 10.3389/fcimb.2020.00030.
  12. Sengupta S, Tang SY, Devine JC et al. Circadian control of lung inflammation in influenza infection. Nat Commun 2019 Sep 11;10(1):4107. doi: 10.1038/s41467–019–11400–9.
  13. Jester BJ, Uyeki TM, Patel A, Koonin L, Jernigan DB. 100 Years of medical countermeasures and pandemic influenza preparedness. Am J Public Health. 2018 Nov;108(11):1469–1472. doi: 10.2105/AJPH.2018.304586.
7.9K 7.9K claps

Dr. Richard Hobday is an internationally recognized authority on health in the built environment.

[Mar 22, 2020] It seems that chloroquine and its use as a 'potent inhibitor of the coronavirus infection' has been known for a long time - since August 2005

Mar 22, 2020 | www.moonofalabama.org

alaric , Mar 22 2020 3:26 utc | 84

I see nothing wrong with testing Hyrodroxychloroquine together with azithromycin as long as its done safely and ethically to gain additional data. If it doesn't work, it doesn't work.

A lot of people are going to reject it just because it came from Trump's mouth. Drug companies will fight against it because they'd rather sell more expensive drugs.

Anti malaria drugs are part of the primary or secondary treatment recommendations in China and Korea. I'm pretty sure they were used in Japan as well so the first half of it (hydroxychloroquine) seems pretty legit though maybe not effective enough. Lets see what happens. I'd agree we lack sufficient data to make an adequate evaluation. Hydroxychloroquine is also being used with other things in trials. We'll see what happens there too.

** A dutch professor has announced an aerosol version of i believe hydroxycholoquine but it might just be chloroquine that is able to penetrate the lungs they claim. They also claim it can be manufactured immediately.

https://www.rtvnoord.nl/nieuws/220259/RUG-onderzoekt-effect-malariamedicijn-op-corona


ted01 , Mar 22 2020 4:03 utc | 87

It seems that chloroquine and its use as a 'potent inhibitor of the coronavirus infection' has been known for a long time - since August 2005.

https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69

No money for big pharma therefore no interest.
They would rather let people die.

alaric , Mar 22 2020 4:19 utc | 88
We should all certainly be skeptical of such a small study (HCQ and azithromycin) but do keep in mind that you really can't trust industry and their legion of paid doctors and experts either.

For example:

The CEO of Ericsson once said "CDMA will never work." Maybe that was because Ericsson didn't have it working for cellular systems at the time. I worked in the cell phone industry as an analyst for some time. People say anything to sell their stuff. I'm sure pharma is equally bad.

Peter AU1 , Mar 22 2020 4:35 utc | 92
ted01 "No money for big pharma therefore no interest. They would rather let people die."

That is about it. A dirt cheap generic drug can't possibly be any good. A pity so many here prefer to believe big pharma rather than the frontline doctors using it.

Peter AU1 , Mar 22 2020 5:02 utc | 94
Chinese doctors Chloroquine or Chloroquine Phosphate - Formula C18H26ClN3
Trump Hydroxychloroquine - Formula C18H26ClN3O

Two different chemicals but I take it their mode of action is similar.

Hydroxychloroquine

"The wholesale cost in the developing world is about US$4.65 per month as of 2015, when used for rheumatoid arthritis or lupus.[7] In the United States the wholesale cost of a month of treatment is about US$25 as of 2020" (wikipedia)

Chloroquine Phosphate

"The wholesale cost in the developing world is about US$0.04.[9] In the United States, it costs about US$5.30 per dose." (wikipedia)

Easy to see why Trump and big phama don't like Chloroquine.

Richard Steven Hack , Mar 22 2020 8:55 utc | 112
Link to a review of available evidence for chloroquine treatments cited:

A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19
https://www.sciencedirect.com/science/article/pii/S0883944120303907?via%3Dihub

Click the PDF link at the top of the page. 5 Pages.

Peter AU1 , Mar 22 2020 9:36 utc | 117
This from link @ Richard Steven Hack | Mar 22 2020 8:55 utc | 114

"chloroquine was highly effective in reducing viral replication, with an Effective Concentration (EC)90 of 6.90 μM that can be easily achievable with standard dosing, due to its favourable penetration in tissues, including in the lung"

Veritas X- , Mar 22 2020 9:41 utc | 119
re: Jackrabbit | Mar 22 2020 6:46 utc @ 106

You may find the following, interesting:

>>>
Brasco_Aad
@Brasco_Aad
Israeli Pharmaceutical Company Teva to send 10 million doses of hydroxychloroquine to the United states, free of charge. | The Times of Israel
Quote Tweet
Brasco_Aad
@Brasco_Aad
· Mar 20
-significant-

Swiss pharmaceutical company Novartis to donate 130 million doses of hydroxychloroquine to the United States.

50 million doses now and another 80 million doses by the end of may.

Enough to treat millions of Americas who have been infected with COVID-19 | Reuters
12:09 AM · Mar 21, 2020
https://twitter.com/Brasco_Aad/status/1241139799077117952
<<<

I don't have the time nor need to try to do any 'confirmation'.
Regards X- in Sweden

Peter AU1 , Mar 22 2020 9:57 utc | 122
Chloroquine I have noticed is also called chloroquine phosphate. Phosphate I believe is the binder that holds the chloroquine powder in tablet form. According to the paper linked by RSH @114 there is 300mg of chloroquine in a 500mg chloroquine phosphate tablet.

[Mar 22, 2020] A pretty good overview on the major avenues to attack nCOV/COVID-19 from a treatment perspective

Mar 22, 2020 | www.moonofalabama.org

c1ue , Mar 22 2020 14:05 utc | 171

Here's a pretty good overview on the major avenues to attack nCOV/COVID-19 from a treatment perspective: Ars Technica overview

In particular, this article talks about targeting different aspects of the nCOV life cycle and how these are targeted by treatments to attack nCOV:
1) Reproduction: remdesivir and others
2) [viral] protein processing: protease inhibitors such as HIV drugs
3) [viral] packaging: attack the final protein packaging of the virus such as a Hep B treatment - but very few such examples exist, of any kind
4) viral shell: plasma distilled from existing recovered victims used to prime immune system of ongoing infected. Vaccines will eventually enable this via manufacturing processes.
5) new infection capability: chloroquines. In particular

One of these targets is the drop in pH. This is the step that's targeted by chloroquine, the antimalarial drug. Chloroquine can cross membranes and so can enter the sac containing the virus. Once there, it can neutralize the pH.

That's significant, because many proteases are only active at lower pH. If the pH inside the sac doesn't change, it's possible that the coronavirus spike protein won't be cut and thus won't be activated. This appears to be the case in cultured cells infected by the virus, and there are anecdotal case reports of chloroquine helping COVID-19 patients.


It is also clear - from this description - why evolutionary pressures could create defenses against this type of attack (chloroquine pH change)

Again, a theoretical operation, even the clinical test tube trials, doesn't equate to effective therapy.
However, IMO, the cost and risk factor for chloroquines makes for a far better gambit than anything else at this moment in time. And note that because of the way chloroquines are supposed to affect nCOV - if chloroquines work, they have to be taken when symptoms first appear or potentially even as a preventative.
I would discourage the preventative use though - that will likely accelerate the nCOV evolution around the chloroquine pH attack.

Another reason: it appears the US only has 160,000 ventilators available Johns Hopkins estimate
of which a bit under 30K are being used for neonatal/pediatric care.
Yow.

Walter , Mar 22 2020 14:15 utc | 174

hydroxycloroquine overdose, the boffins say, can destroy the retina of the eyes.

Not a trivial side effect. Nothing to play with. Fer what it worth, better read up on the drug and pay attention. Eyes are nice to have.

Overdose of Q is Bad.

Wally read 60 years ago in Rome newspaper story that British air-line pilots, who drank their Gin an' Tonics, had been discovered to have very poor glare recovery. That, they said, was from the quinine in the tonic water. Henceforth, they were forbidden the tonic water, alas!

But Wally never drives at night and his airplane days ended back in the mists...

He's saving the quinine he's got, for now.

[Mar 22, 2020] Equivalent respirator standards by country

Mar 22, 2020 | www.moonofalabama.org

Peter AU1 , Mar 21 2020 22:18 utc | 44

Equivalent respirator standards by country
. N95 (United States NIOSH-42CFR84)
• FFP2 (Europe EN 149-2001)
• KN95 (China GB2626-2006)
• P2 (Australia/New Zealand AS/NZA 1716:2012)
• Korea 1st class (Korea KMOEL - 2017-64)
• DS (Japan JMHLW-Notification 214, 2018)

I just received an email from a contact in China offering to help get FFP2 respirators if I needed or wanted any. She said KN95 were virtually non existent in China but there are limited supplies of the FFP2 respirators.

TJ , Mar 21 2020 22:29 utc | 47

@44 Peter AU1

If you or anyone else is interested in masks / respirators I would recommend watching the videos by weaponsandstuff93 on YouTube. I am no expert on the subject but on his recommendation I got myself a mask that takes 40mm NATO filters ( the mask is a Belgium BEM4 ) and some P3 level filters ( mine are Scott Pros ) this is different to 40MM GOST filters which were the Soviet standard.

[Mar 22, 2020] Make your own face masks?

Mar 22, 2020 | www.moonofalabama.org

Ian2 , Mar 21 2020 21:04 utc | 26

Make your own face masks? Pfff...it appears the Japanese found a better idea from the Philippines government... panties . OR, you could order a custom one from Pantsu Mask . ROFL

[Mar 22, 2020] WTO stance on Covid-19 propaganda and manipulation

Returning to the Covid-19 epidemic and the way governments are reacting to it, Thierry Meyssan stresses that the authoritarian decisions of Italy and France have no medical justification. They contradict the observations of the best infectiologists and the instructions of the World Health Organization.
Mar 22, 2020 | www.voltairenet.org

In all of its messages, the WHO stressed : the low demographic impact of the epidemic; the futility of border closures; the ineffectiveness of wearing gloves, masks (except for health care workers) and certain "barrier measures" (for example, the distance of one metre only makes sense with infected people, but not with healthy people); the need to raise the level of hygiene, including hand washing, water disinfection and increased ventilation of confined spaces. Finally, use disposable tissues or, failing that, sneeze into your elbow.

However, the WHO is not a medical organization, but a United Nations agency dealing with health issues. Its officials, even if they are doctors, are also and above all politicians. It cannot therefore denounce the abuses of certain states. Furthermore, since the controversy over the H1N1 epidemic, the WHO must publicly justify all its recommendations. In 2009, it was accused of having let itself be swayed by the interests of big pharmaceutical companies and of having hastily sounded the alarm in a disproportionate manner [ 4 ]. This time it used the word "pandemic" only as a last resort, on March 12th, four months later.

[Mar 21, 2020] Air pollituion as an important factor in this virus epidemic

Mar 21, 2020 | www.moonofalabama.org

Allen , Mar 22 2020 1:06 utc | 68

I urge everyone to read the first article that is linked. What is happening this year is decidedly NOT a unique phenomenon for Italy or elsewhere that has been cited below. You might call it an acceleration or culmination or "perfect storm" but this is not a unique situation.

I wish to stress the following:

Estimated excess deaths of 7,027, 20,259, 15,801 and 24,981 attributable to influenza epidemics in the 2013/14, 2014/15, 2015/16 and 2016/17 seasons in Italy.

Anyone remember a global outcry about these excess deaths during any of these years?

Pollution; The Po river contains some of the worst waste from industrial pig farms upriver. The air quality in the Po River Valley is some of the worst only behind an area in Poland where they still use coal fired power plants in overall poor quality.

The people in N Italy have been subjected to constant bombardment of this pollution which destroys their respiratory functions and weakens their immune systems- a perfect milieu for viruses to proliferate. The same is true for those in N China and Tehran. Tehran's air quality has deteriorated dramatically since the US sanctions as they have gone to using a cheaper gas, laced with sulfur, to provide fuel for their people.

Northern Italy has one of the oldest populations and the worst air quality in Europe, which has already led to an increased number of respiratory diseases and deaths in the past and is likely an additional risk factor in the current epidemic.

According to the latest data of the Italian National Health Institute ISS, the average age of the positively-tested deceased in Italy is currently about 81 years. 10% of the deceased are over 90 years old. 90% of the deceased are over 70 years old.

The Italian Institute of Health moreover distinguishes between those who died from the coronavirus and those who died with the coronavirus. In many cases it is not yet clear whether the persons died from the virus or from their pre-existing chronic diseases or from a combination of both.

This is not a coincidence that these environmental factors have created a milieu in which all sorts of diseases can proliferate. Now capitalism will come up with the magic bullet like a vaccine or a pill to "fix" the problem- rinse and repeat if the current social order/forms of production aren't radically changed.

A virus which impacts upper respiratory functions attacking those who are vulnerable due to years of having their upper respiratory systems assaulted non-stop by heavy doses of pollutants of all varieties- that's what we are seeing. None of this is new except to the degree. In all the areas listed below, N Italy, N China, Madrid, Tehran they have been experiencing a dramatic increase in upper respiratory disease for years now.

And please don't tell me the solution is some vaccination or some great new cure that will be discovered (and profited from) by the miraculous men of modern medicine. The solution is to clean up the environment so that we are not vulnerable in the first place. Without that prepare for COVID-20 the sequel or whatever name the thoroughly bought off WHO and CDC and...wish to place upon this next "pandemic."

Investigating the impact of influenza on excess mortality in all ages in Italy during recent seasons (2013/14–2016/17 seasons)

In recent years, Italy has been registering peaks in death rates, particularly among the elderly during the winter season. Influenza epidemics have been indicated as one of the potential determinants of such an excess.

We estimated excess deaths of 7,027, 20,259, 15,801 and 24,981 attributable to influenza epidemics in the 2013/14, 2014/15, 2015/16 and 2016/17, respectively, using the Goldstein index. The average annual mortality excess rate per 100,000 ranged from 11.6 to 41.2 with most of the influenza-associated deaths per year registered among the elderly.

https://www.ijidonline.com/article/S1201-9712(19)30328-5/fulltext

Nitrogen dioxide and fine particles are threatening Po valley air quality

https://vitesy.com/blog/air-pollution/nitrogen-dioxide-fine-particles-po-valley-air-quality/

Italy's polluted Po Valley gasps for fresh air

https://phys.org/news/2019-02-italy-polluted-po-valley-gasps.html


How a 'Toxic Cocktail' Is Posing a Troubling Health Risk in China's Cities

https://e360.yale.edu/features/how-a-toxic-cocktail-is-posing-a-troubling-health-risk-in-chinese-cities


The new study argues that smogs in China contain more ingredients than those found either in the legendary "pea-soupers" of 19th- and 20th-century Europe and North America or in modern rich-world, vehicle-generated smogs. Something new is happening: The unprecedented speed of industrialization and urbanization has combined two eras of pollution.

Investigating air quality status and air pollutant trends over the Metropolitan Area of Tehran, Iran over the past decade between 2005 and 2014


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044178/

Overall, trends have been progressed to worsening, the number of healthy days has been declined and the number of unhealthy days has been increased in recent years.

Tehran is rated as one of the world's most polluted cities. Parts of the city are often covered by smog, making breathing difficult and causing widespread pulmonary illnesses. ... According to local officials, 3,600 people died in a single month due to the hazardous air quality.

Air Pollution, a Silent Form of Death for Tehran Citizens

https://www.iranfocus.com/en/life-in-iran/34172-air-pollution-a-silent-form-of-death-for-tehran-citizens


Madrid air pollution reaches alarming levels

You don't have to step into the street for Madrid's roads to pose a hazard to your health: air pollution from cars in the city might just knock you over. Scientists are finding links between the gases and disease.

......

According to studies by Julio Diaz, a researcher at the Carlos III Health Institute in Madrid, even small increases in air pollution can cause the number of people admitted to hospitals with circulatory and respiratory illnesses to rise.

https://www.dw.com/en/madrid-air-pollution-reaches-alarming-levels/a-16739363

[Mar 21, 2020] Vietnam is now requiring everyone to wear masks in public places.

Mar 21, 2020 | www.moonofalabama.org

Hope , Mar 22 2020 1:02 utc | 67

There's much attention being given to how China and South Korea have reacted to the virus, but amazingly little to the response in Vietnam. The first cases in Vietnam arrived with the new lunar year, via Wuhan; quite quickly the number of cases rose to sixteen, and for several weeks stayed at that number. The Vietnamese government acted quickly, strongly and effectively, until all sixteen recovered (and the district near Hanoi which had been placed under lockdown had completed their isolation.
On March 2nd a flight from London, carrying a woman who was returning from the Milan fashion week:
"The country's 17th case, imported on a flight from London, kicked off a new wave of cases, [now nearing 100].

Even with a new wave of cases, the numbers are far from those witnessed in the western world. The issue has been taken seriously, with all suffering symptoms put in quarantine and tested, while their places of residence are locked down and sanitised. Việt Nam was one of the first nations to declare an epidemic and has been quick in its response, both in handling current cases and ensuring the spread of the virus is as limited as possible. "
- taken from https://vietnamnews.vn/life-style/expat-corner/653815/keeping-calm-and-carrying-on-viet-nam-sets-a-coronavirus-example.html

It is notable that almost all cases of infection have been brought into the country, or at one-person distance from the person bringing it into the country.

Today there has been the announcement of the seventeenth reported recovery in Vietnam. So far there has been not one death.

Points in the reaction:
Public gatherings were stopped right away - even local community Women's Day lunches.
All citizens and all foreigners are now required to report on health, on recent travel, etc.
Everyone is now required to wear masks in public places.

[Mar 21, 2020] Coronavirus - A Laymans Update By Walrus

Mar 21, 2020 | turcopolier.typepad.com

Larry Kart , 20 March 2020 at 07:57 PM

FWIW, Dr. Fauci pretty much threw cold water on the Chloroquine option at today's Trump press conference, saying that no clinical trials have been conducted and leaving the impression that he was highly dubious. Again, FWIW.

P.S. I wonder how long Fauci will be welcomed onto that podium.

[Mar 20, 2020] No specific vulnerability of East Asians?

Mar 20, 2020 | www.moonofalabama.org

Kassandra , Mar 19 2020 22:00 utc | 201

No specific vulnerability of East Asians?

"The East Asian populations have much higher AFs in the eQTL variants associated with higher ACE2 expression in tissues (Fig. 1c), which may suggest different susceptibility or response to 2019-nCoV/SARS-CoV-2 from different populations under the similar conditions."

This is a "we do not know yet", not a "we can exclude".

No lab-generated strain?

The Furin docking cleavage site has not been found yet in any other beta-CoV strain, it is only known from other completely different viruses and seem to be related there with being highly contagious. In adition, a recent study found a third docking option via GRP78 expressions on the cell surface (usually by cells experiencing stress), https://www.researchsquare.com/article/rs-15157/v1 . This is already two strange features more compared to SARS and MERS.

There is only a "there is no proof, neither a direct hint found yet", not a "we can exclude", but a mere belief.

Most irritating is that there is are not intermediate or other similar strains found yet, and that there is a strange pattern of first occurences in the early phase in Wuhan (and probably also in the US). We still have no sound explanation how it came into existence, not even some plausible facts suggesting a pathway. Given the technical capabilities since 15 years, the multitude of stakeholders working on gene editing, for vaccine research also on dangerous stains, and some irritating cui bono issues, it is too early to discard some suspicions already. The scope of potential perpetrators (by accident or intentionally with a not expected outcome) is broad and - given the very intransparent transnational companies - quite opaque. In issues of global security and extreme relevance for humanity, transparency should be enforced and secrecy for corporate interests should not be tolerated in such cases.

Anyway, most important now is to mitigate the ongoing desaster, we should only not forget some issues for later investigation.


antitermite , Mar 19 2020 22:23 utc | 208

The argument that cov19 isn't engineered because biowar researchers & the empire that incubates them are 1. Sane and 2. Indequately funded
Nope, not buying it on either count.

https://www.globalresearch.ca/the-geopolitical-deployment-of-biological-weapons/5703005

The hegemony has military labs all around the globe (though the Fort Detrick closure is suspicious).

Even if it weren't engineered, a virus doesn't need to be vat-grown to be politically useful - anthrax, smallpox and bubonic plague - all natural & deadly pathogens - exist within bioweapon labs, for research purposes of course.

I am a little doubtful about the wuhan games being the vector - think of the timing, right before CNY.
Surely a "Diplomat" with a diplomatic bag could have a far wider range of opportunities (via proxies) for more precise delivery.

Unlike what other posters here have been reporting, most Chinese markets are quite clean, at least those I've seen. Yes they are certainly diverse. Here's a good example (not Wuhan though)
https://viktoriajean.com/2019/10/25/qingdao-starfish-sea-urchin-and-other-exotic-foods/

bevin , Mar 19 2020 22:32 utc | 209
An interesting story at Common Dreams
"A look at financial records reveal that Senate Intelligence Committee Chairman Sen. Richard Burr last month -- just as he was big-dollar donors, but not the general public about the looming threat of the coronavirus -- personal stock holdings worth hundreds of thousands of dollars, many of them in industries now seriously impacted by the outbreak..."

".....In an audio recording obtained by NPR, the North Carolina Republican was heard telling donors at a luncheon on Feb. 27 that the coronavirus, officially called COVID-19, would likely spread through the population aggressively -- and suggested it could kill hundreds of thousands of people.

"It is much more aggressive in its transmission than anything that we have seen in recent history," Burr said.

"It is probably more akin to the 1918 pandemic," he added, referring to the flu pandemic which killed more than 600,000 Americans...."
There is audio here

https://www.commondreams.org/news/2020/03/19/while-warning-donors-reassuring-public-gop-intel-chair-unloaded-personal-stocks

Bongocero , Mar 19 2020 22:41 utc | 215
Here is the patent application filed in 2004 showing that the virus was invented in a lab: https://patentimages.storage.googleapis.com/e0/4e/2e/09e238c87e2d20/EP1694829B1.pdf
H.Schmatz , Mar 19 2020 22:43 utc | 216
Really, it is hard stop thinking this was a preplanned event...

Wall Street is pressuring key healthcare firms to hike prices over the coronavirus crisis. Audio here of bankers asking drug companies, firms supplying N95 masks & ventilators, to figure out how to profit from the Covid-19 emergency.

https://twitter.com/lhfang/status/1240716348939833344

karlof1 , Mar 19 2020 22:50 utc | 217
Today's Keiser Report declares petrodollar and fiat dollar dead and announces the world will need to have a confab to arrange a new commercial currency or currency basket. Other interesting food for thought's discussed. The 2nd half interview is with a metals broker who says we must demand physical delivery instead of paper because the derivatives aren't properly reflecting physical price. An item from Shadowstats's Daily Update, "the February 2020 Cass Freight Index® Continued in Annual Decline for the 15th Straight Month, Down by 7.5% (-7.5%)," further ongoing confirmation that we've actually been in a recession for at least that long.
Mao , Mar 19 2020 23:07 utc | 221
In the wake of the coronavirus outbreak, investors who bought "pandemic bonds" from the World Bank in 2017 are set to lose hundreds of millions of dollars.

https://www.youtube.com/watch?v=TbfWuk1r6dY

vk , Mar 19 2020 23:17 utc | 223
It seems people here don't understand the concept of "burden of proof".

Burden of proof arives from a logical necessity. If you treat every hypothesis existent in the universe for which there are no scientific evidence as a priori true, the it would mean they are all true at the same time. The same if you treat them as all false.

That, of course, would be a logical fallacy, since contradictory hypotheses would be true or false at the same time.

That's why the absence of evidence the SARS CoV-2 isn't a bioweapon doesn't make it a bioweapon. Since we don't know that, that would make, by the same logic, it a bioweapon and a not-bioweapon at the same time. It is the same fallacy of religion: you can't prove God doesn't exist (and you really can't, since God is a metaphysical concept, not a physical one), therefore it must exist in the eyes of the religious.

Except that, in the case here, there is strong evidence the SARS CoV-2 is fruit of evolution, so I don't even know why people are bringing the opposite hypothesis here without even a hint of evidence.

Pft , Mar 19 2020 23:25 utc | 224
"Some Indian researchers found four genome sequences in the novel coronavirus that can also be found in the HIV virus. They self published their findings in a paper that was not peer reviewed. We discussed that paper in detail on February 1 in our second post on the virus and we strongly expressed our doubt about its veracity. A few days later the paper was retracted by its authors after other scientists had pointed out that the lengths of each of the four sequences they had compared were way too small to be of statistical significance."

The authors retracted the study temporarily to allow it to be peer reviewed. They did not concede their results were insignificant. The stated reason for retracting the study from one of the authors is because the study was being used to promote conspiracy theories that the virus was intentionally released as weapon since they made no such contention

"Asian people are not more genetically receptive for the novel coronavirus."

Yet the study you linked to states "The East Asian populations have much higher AFs in the eQTL variants associated with higher ACE2 expression in tissues (Fig. 1c), which may suggest different susceptibility or response to 2019-nCoV/SARS-CoV-2 from different populations under the similar conditions."


There is zero evidence that the virus is from a Chinese or U.S. or other (weapon) laboratory and the claim actually makes no sense. The genome of the virus consists of more then 23,000 'letters'. It is significantly different than the genome of other known viruses."

Absence of evidence is not evidence of absence. Actually, its pretty similar to the bat virus found in 2013 as reported by Shi Zheng Li in January , 2020. And the key word is "known". How stupid would you have you have to be to publish the sequence data in public papers of the exact virus that will be used as a weapon before unleashing the virus. Shi Zhengli was involved in gain of function research for over a decade working with Ralph Baric at UNC on some research.

If you look at the research thats been done on corona viruses gain of function and corona virus/ebola/zika virus vaccines you run into the same names a lot, Chinese scientists like Shi Zhengli, American scientists like Ralph Baric of UNC, Wuhan institute of Virology/BSL-4 lab, ,Duke University and USAMRIID, both of which has ties with Wuhan University-Institute of Medical Virology all funded by USAMRIID, DARPA, NIAD, BARDA, NIH , chinese military, chinese CDC, Bill Gates (WHO, Event 201, AMC, CEPI) , and various vaccine makers such as Innovio, Moderna, NanoViricides, etc, often in collaboration with each other. George Gao of China CDC attended Event 201.

Look close at Project Bioshield-The Department of Homeland Security uses intelligence reports to decide which diseases and biological threats are considered "material," or realistic threats to US security. It then refers these findings to Health and Human Services (HHS), which determines whether it's necessary for the government to order new drugs from pharmaceutical companies to combat the threats.

A funding agency within HHS called the Biomedical Advanced Research and Development Authority (BARDA) hands out lucrative contracts for research, parts of which can be paid up front.

The parent agency (HHS) in charge of funding drugs and vaccines for the national stockpile, is also the one that is separately funding research into new diseases that could result in a bioterror or accidental infection, which would in turn demand a response from the national stockpile. Sounds like a racket

More on Ralph Baric- also known as the Godfather of Corona Virus due in part to a corona virus vaccine patent in 2002 as well as his subsequent research. But Dr. Ralph Baric's lab
is designed to develop drugs against new emerging pathogens focuses on coronaviruses. Baric and his 30-person team partnered with Gilead Sciences, Inc. six years ago to test antiviral drugs such as Remdesivir to curb emerging viral diseases that were then largely overlooked by big pharmaceutical companies.

Gilead Science as you recall struck gold with Tamiflu thanks to Bird Flu scares that followed after SARS. Also known for its association with Donald Rumsfeld.


[Mar 20, 2020] Looks like COVID-19 is more contagious then evne Spalish flu

Mar 20, 2020 | www.moonofalabama.org

S , Mar 20 2020 2:08 utc | 263

PokeTheTruth #150:
Also there is no proof that COVID-19 is "more contagious" either by laboratory analysis or in fielded studies than influenza. If you know of such a paper, I would appreciate a link so that I can examine it for myself.

From the Wikipedia article " Basic reproduction number " (see the article for references):

    Disease                           R0

    COVID-19                          1.4–3.9
    Influenza (1918 pandemic strain)  1.4–2.8
    Influenza (2009 pandemic strain)  1.4–1.6
    Influenza (seasonal strains)      0.9–2.1

More comparisons between COVID-19 and influenza: How does the new coronavirus compare with the flu? ( Live Science ).

[Mar 20, 2020] Virus and air pollution

Mar 20, 2020 | www.moonofalabama.org

Jen , Mar 19 2020 20:17 utc | 162

James @ 47:

There have been articles posted online about high levels of air pollution in Italy's Po River valley region, where Lombardia province is located. Do a search on Google or DuckDuckGo and they appear.

Much of that pollution probably occurs at particular times of the year. Milan is said to be notorious for temperature inversions, as is Tehran in Iran. These occur in winter-time in Tehran nearly every year. Cold air sinks under warm air in river valleys or inter-mountain valleys and plateaux so air is trapped and cannot circulate, trapping pollutants. Milan, Tehran and probably Wuhan beside the Jiangzi River sit in these kinds of physical environments.

Italy does seem to have a history of industrial accidents. I have a double CD set of urban folk by Alessandro Monti, "Unfolk + Live Book", which is partly inspired by an industrial poisoning incident that occurred somewhere in northern Italy in the 1970s. Can't remember any details and can't look up now, being on smartphone, but it was a major incident, large numbers in the vicinity were poisoned, many died and others still struggling with long-term effects. May have been some form of dioxide poisoning.

[Mar 19, 2020] US bad availability actually isn't bad: there are spots where 20% infection in 12 months is bad, but overall the US seems in decent shape

Mar 19, 2020 | www.moonofalabama.org

c1ue , Mar 19 2020 17:48 utc | 95

Propublica has published a model showing hospital bed availability vs. nCOV infection rates, nationwide: bed vs. infection rate
It actually isn't bad: there are spots where 20% infection in 12 months is bad, but overall the US seems in decent shape. 20% in 6 months - significant red coverage.

But interestingly - my Eyeball Mark I shows the negative effects mostly in the liberal zones = cities.

[Mar 19, 2020] All the funny videos about Chinese making masks out of women's bras, water bottles: not so funny now

Mar 19, 2020 | www.moonofalabama.org

c1ue , Mar 19 2020 17:44 utc | 93

All the funny videos about Chinese making masks out of women's bras, water bottles: not so funny now: Washington hospital making masks out of office supplies

And people are really saying there weren't racist currents?

[Mar 19, 2020] Chloroquine/hydrochloroquinine was determined to be effective for the treatment of the coronavirus by Chinese clinicians early in February, and the Chinese government announced this on February 17 this year.

Mar 19, 2020 | www.moonofalabama.org

Jack R , Mar 19 2020 16:33 utc | 58

Chloroquine/hydrochloroquinine was determined to be effective for the treatment of the coronavirus by Chinese clinicians early in February, and the Chinese government announced this on February 17 this year. Today (March 19) Trump and his staff amazingly announced that medical personnel in American health agencies have discovered, developed and were testing these drugs without any mention of the considerable Chinese, as well as Korean, published experience and success using these closely-related and relatively safe malarial drugs. Shameful and highly deceitful, to say the least. This deceit should be revealed again and again without letup.

[Mar 19, 2020] Do not fall for the barrage of fake news in the Western MSM about "promising cures, treatments and vaccines" coming from some alleged geniuses at some unicorn in some First World country:

Mar 19, 2020 | www.moonofalabama.org

Noirette , Mar 18 2020 18:18 utc | 50

TJ @ 3, adding:

Chloroquine was proposed as an efficient anti-viral for Cov-19 (short for the virus and disease) by Dr. Raoult in France, right from the start. He is supposedly the no.1 expert *World* on Communicable diseases. See list of names in the > right column.

http://expertscape.com/ex/infectious+diseases

This type of grading - ranking - endorsing, certifying, etc. some 'experts', does NOT per se correlate with their knowledge, honesty, ingenuity, insight (which may be random), etc. It is very much a social acceptance by the PTB scene based on no. of publications, contacts, financial awards, contacts with pols, getting more funding, being able to run a team, etc.

Yet, Dr. Raoult (Marseilles) is not in F considered a great expert at all, as he is not part of the Paris-Nexus.

https://www.connexionfrance.com/French-news/French-researcher-in-Marseille-posts-successful-Covid-19-coronavirus-drug-trial-results

This short clip 4 mins on Jan. 21, he is questioned about the coronaviruses (well before huge alarm in F) shows the personage. In F no subs, but have a look-see for 30 secs.

https://youtu.be/qoBoryHuZ6E

Here he explains why chloroquine can treat Cov-19 infections. In F.

https://youtu.be/fcNRmALkpTA

Imho several anti-virals will turn out to have some supressive / effective action, just like for HIV.


TJ , Mar 18 2020 18:35 utc | 55

Coronavirus Pandemic Update 39: Rapid COVID-19 Spread with Mild or No Symptoms, More on Treatment from MedCram about the French using chloroquine to treat patients with COVID-19.
JC , Mar 18 2020 19:16 utc | 62
Weekly Monday-Wednesday-Friday. Live from WHO Headquarters

"Live from WHO Headquarters - COVID-19 daily press briefing 18MAR2020"


https://www.youtube.com/watch?v=wucieL5YxCs

vk , Mar 18 2020 19:24 utc | 64
@ Posted by: donkeytale | Mar 18 2020 18:49 utc | 61

Did you see my link? Japan has a daily test capacity of only some 7,000 (South Korea, for example, is testing 20,000 per day). To make things worse, it is using just one sixth of this capacity. My source is the Japan Times, so you cannot invoke propaganda.

The Chinese doctors are using at least 22 different broad-spectrum antivirals to try to treat the infected. Not surprised one of them is Japanese, but that's irrelevant information (one of them, for example, is Cuban).

As I've posted in the previous thread, in moments of pandemic crisis against a disease without cure, doctors on the field have the poetic license to try whatever they want to. So they threw practically everything in Wuhan (shots in the dark after shots in the dark). It's acceptable medical practice in these extraordinary cases.

But none of the 22 antivirals are cures. Not even close. Best case scenario, they gain some time for some patients. Do not fall for the barrage of fake news in the Western MSM about "promising cures, treatments and vaccines" coming from some alleged geniuses at some unicorn in some First World country:

Zhong Nanshan: No evidence that COVID-19 originated in Wuhan

Zhong made the remarks at a press conference in Guangzhou on Wednesday, stressing that so far there is no targeted therapeutic COVID-19 drug and international cooperation is still needed for new experiments.

The fight against the COVID-19 should not be reliant on "herd immunity," Zhong added, saying that the production of an effective COVID-19 vaccine is at present the top priority, and the development requires international cooperation.

Zhong also made very clear the laissez-faire tactic won't work:

"There is no evidence of immunity for life after one infection of the virus," Zhong added.

[Mar 19, 2020] Virus and air quality

Mar 19, 2020 | www.moonofalabama.org

Jen , Mar 18 2020 20:25 utc | 77

Ken Garoo @ 43:

Iran (especially Tehran), northern Italy (Po River valley region) and Wuhan are also areas of high levels of air pollution. Populations in these regions are located in river valleys or plateaux in mountainous areas where temperature inversions leading to thick smog are common. I've read that Tehran experiences annual temperature inversions once a year, in the past occurring in December but in recent times starting earlier in November. Qom, where Iran's COVID-19 outbreak started, is not far from Tehran and itself is becoming more industrialised.

Northern Italy is reputed to have the worst air quality of any region in Europe.

jayc , Mar 18 2020 20:49 utc | 82

Interesting that there was a flood of comments yesterday - here, at Off Guardian, and other similar sites - all pushing the concept that the virus is a mild flu and that best practices, particularly social distancing, were in fact a scam designed to initiate the new world order/global police state, or something. Rational responses were met with all-caps freak outs and down-voting.

In my area, vehicle traffic has been down by at least 50%. The skies are noticeably clearer. A colleague pointed out that satellite imagery over northern Italy has shown that the air quality there has visibly improved.

[Mar 19, 2020] SK doctors have been using the malaria/arthritis drug hydrochloroquine to treat patients with much success, now a doctor in France has found that a combination of that drug and a common antibiotic azithromycin has cured up to 70% of patients after 3 to 6 days

Mar 19, 2020 | www.unz.com

Anon [279] Disclaimer , says: Show Comment March 19, 2020 at 1:56 am GMT

People should take a closer look at the stats coming out of Germany and S. Korea, both countries known for extensive testing. There are over 8,100 cases in Germany, yet death remains at 12, which makes the death rate <0.15%, almost on par with the flu. SK's death rate is around 0.65%.

SK doctors have been using the malaria/arthritis drug hydrochloroquine to treat patients with much success, now a doctor in France has found that a combination of that drug and a common antibiotic azithromycin has cured up to 70% of patients after 3 to 6 days:
https://dailycaller.com/2020/03/18/hydroxychloroquine-coronavirus-covid19-cure-study/

Hopefully this is the cure we've been waiting for.

[Mar 17, 2020] Which objects to sanitize to avoid spreading the deadly disease

Notable quotes:
"... our own hands can be the biggest culprit when it comes to adding germs and bacteria onto your phone. ..."
"... mobile telephones are particularly dirty because people do not necessarily wash their hands before touching them. ..."
"... Shaking hands is a frequent transmission route for disease in hospitals. ..."
Mar 17, 2020 | express.co.uk
...Express.co.uk has compiled advice to show which objects to sanitise to avoid spreading the deadly disease. Trending
Mobile phones

Research has found mobile phones can be 10 times dirtier than toilet seats. Your own hands can be the biggest culprit when it comes to adding germs and bacteria onto your phone.

Assistant professor of epidemiology at the University of Michigan School of Public Health, Emily Martin, said mobile telephones are particularly dirty because people do not necessarily wash their hands before touching them.

She told Time.com: "Because people are always carrying their cell phones even in situations where they would normally wash their hands before doing anything, cell phones do tend to get pretty gross."

ATMs or ticket machines

Ticket machines and ATMs will be touched by many people which means it poses a risk to spreading coronavirus.

Coronavirus warning: Coronavirus has killed more than 94,000 people around the world (Image: GETTY) Telephones

Your mobile phone can pose a risk, but additionally so can shared office telephones.

Office kitchens

Coffee machines or kettles will be handled by multiple people, so it's a good idea to use hand sanitiser after doing the tea round.

Lift buttons

Lift buttons can be touched by potentially hundreds or thousands of people depending on how many people use the lift regularly.

This means it can pose a threat to spreading coronavirus.

Handrails

Escalators, tube handrails, bannisters will all be touched constantly, potentially by thousands of people a day.

Dr Tait-Burkard told the Guardian: "If you're on public transport, there's no way not to touch the handrails.

"So when you get off, disinfect your hands."

Coronavirus warning: More than 75 countries have reported cases of coronavirus (Image: GETTY) Communal bathrooms

Communal bathrooms can pose a threat as they are enclosed spaces which will be accessed by several people.

The door handles, soap dispensers, hand dryers, bins and other objects could be touched by many people.

Additionally, people often blow their noses in the bathroom which can help spread the virus.

Hospitals

Hospitals can be hotbeds for disease, so it is advisable to wash your hands thoroughly before and after visiting a hospital.

Professor Haas told the Guardian: "Shaking hands is a frequent transmission route for disease in hospitals.

"It's why health personnel are supposed to regularly disinfect their hands."

[Mar 17, 2020] In might make sense to wash you nose with saltwater. To gaggle you throat with the mouth wash.

There is only limited evidence to suggest it actually helps. However, saltwater rinses have not been shown to prevent respiratory infections in the past. The NHS said: “There is no evidence that regularly rinsing the nose with salt water protects you from coronavirus”. The real question is how long it take the virus to get inside the cell: is this hours or minutes?
BTW Research has found mobile phones can be 10 times dirtier than toilet seats.
Gargling with slat war is probably completely false: FALSE Gargling salt water ‘eliminates’ coronavirus
The use of saline (salt water) irrigations for the nose and sinuses has been shown to be highly effective in improving allergy symptoms and shortening the duration of a sinus infection. Typically, for allergy sufferers, doctors recommend irrigating the sinuses once every day to every other day with 8 ounces of salt water. Make your own saline rinse Combat sinus infections
Mar 17, 2020 | www.moonofalabama.org
Stonebird , Mar 17 2020 20:33 utc | 25

As an Asthmatic I found this information interesting. You might need to scroll down - as simple solutions (mainly before you really get it !) are near the end.

https://thesaker.is/how-to-treat-coronavirus-infection-covid-19/

Quotes; A: Are you asking for some simple recommendations? First of all, take a good care for the nasal mucosa and oropharyngeal area.

Q: To wash it with saltwater?
A: Yes, wash it thoroughly. But "lors" – non-prescription medications and sinus cleaners to stop running nose and for an effective lavage. That is, the feeling of free unobstructed breath should come after all. The second thing is the oropharyngeal area behind the uvula. And there, too, you need to make a good lavage of the oropharyngeal region.

Q: So you don't just have to squirt it up your nose, you have to gargle it deep down your throat?
A: Yes, and rinse it out. And don't be lazy. Do do it until you get a feeling of clean, good airways. Of all the ways, this is the most effective. I would advise those people who can afford to buy a nebulizer or

Q: Do you mean, it's aerosol, right? With ultrasound?
A: Yes. And it allows the hygiene of the upper respiratory tract to be brought to a good state. When a cough starts, it is desirable to still apply the medications that we prescribe for patients with bronchial asthma. This is either Berodual, or Ventolin, or Salbutamol. Because these drugs improve mucociliary clearance, relieve spasm.

Q: You mean expectorant?" Mucolytic ACC?
A: Yes, ACC and Fluimucil. And what you can't do is use glucocorticosteroids. This virus replication is rapidly increasing by them.

Q: What does that mean?
A: Corticosteroids is prednisone, methylprednisolone, dexamethasone, betamethasone.

Q: So you don't need to inject hormones, relatively speaking, if you have a viral infection?
A: There are inhaled steroids. But there are patients with asthma who are ill and are on this therapy. But this has to be a tailor-made solutions.

------------

b's and most western Government's change of heart, makes sense if the re-infection rate is much higher and more lethal than the first onset of the virus. I don't know the truth about this but there was a small, quickly suppressed, report from *researchers* in Hubei that this is the case. The second time round we are talking about an attack on the "vital" organs (heart etc) in a relatively short period of days.

What will happen is a societal collapse, or a total financial scam where the billionaires come out of hiding and take everything for a few shekels. Remember that debts can be "claimed" decades after they are made. So ordinary people will have to pay back all these massive "aids" later, through taxes.

Richard Steven Hack , Mar 17 2020 20:57 utc | 34

@Stonebird | Mar 17 2020 20:33 utc | 25

I keep seeing people recommending this salt water lavage. So I looked it up on the Internet. No, it does *not* kill the virus. It might ease the symptoms, but does nothing to eliminate the virus.

As far as I know from reading so far, there are *no* "home remedies" that can deal with this virus.

I have seen suggestions to boost your vitamin intake in hopes of boosting your immune system. I've upped my C to 3 grams a day instead of my usual 1 and my D-3 to 6,000 units instead of my usual 4,000.

[Mar 17, 2020] First of all, take a good care for the nasal mucosa and oropharyngeal area.

Mar 17, 2020 | www.moonofalabama.org

Stonebird , Mar 17 2020 20:33 utc | 25

As an Asthmatic I found this information interesting. You might need to scroll down - as simple solutions (mainly before you really get it !) are near the end.

https://thesaker.is/how-to-treat-coronavirus-infection-covid-19/

Quotes; A: Are you asking for some simple recommendations? First of all, take a good care for the nasal mucosa and oropharyngeal area.

Q: To wash it with saltwater?
A: Yes, wash it thoroughly. But "lors" – non-prescription medications and sinus cleaners to stop running nose and for an effective lavage. That is, the feeling of free unobstructed breath should come after all. The second thing is the oropharyngeal area behind the uvula. And there, too, you need to make a good lavage of the oropharyngeal region.

Q: So you don't just have to squirt it up your nose, you have to gargle it deep down your throat?
A: Yes, and rinse it out. And don't be lazy. Do do it until you get a feeling of clean, good airways. Of all the ways, this is the most effective. I would advise those people who can afford to buy a nebulizer or

Q: Do you mean, it's aerosol, right? With ultrasound?
A: Yes. And it allows the hygiene of the upper respiratory tract to be brought to a good state. When a cough starts, it is desirable to still apply the medications that we prescribe for patients with bronchial asthma. This is either Berodual, or Ventolin, or Salbutamol. Because these drugs improve mucociliary clearance, relieve spasm.

Q: You mean expectorant?" Mucolytic ACC?
A: Yes, ACC and Fluimucil. And what you can't do is use glucocorticosteroids. This virus replication is rapidly increasing by them.

Q: What does that mean?
A: Corticosteroids is prednisone, methylprednisolone, dexamethasone, betamethasone.

Q: So you don't need to inject hormones, relatively speaking, if you have a viral infection?
A: There are inhaled steroids. But there are patients with asthma who are ill and are on this therapy. But this has to be a tailor-made solutions.

------------

b's and most western Government's change of heart, makes sense if the re-infection rate is much higher and more lethal than the first onset of the virus. I don't know the truth about this but there was a small, quickly suppressed, report from *researchers* in Hubei that this is the case. The second time round we are talking about an attack on the "vital" organs (heart etc) in a relatively short period of days.

What will happen is a societal collapse, or a total financial scam where the billionaires come out of hiding and take everything for a few shekels. Remember that debts can be "claimed" decades after they are made. So ordinary people will have to pay back all these massive "aids" later, through taxes.

Richard Steven Hack , Mar 17 2020 20:57 utc | 34

@Stonebird | Mar 17 2020 20:33 utc | 25

I keep seeing people recommending this salt water lavage. So I looked it up on the Internet. No, it does *not* kill the virus. It might ease the symptoms, but does nothing to eliminate the virus.

As far as I know from reading so far, there are *no* "home remedies" that can deal with this virus.

I have seen suggestions to boost your vitamin intake in hopes of boosting your immune system. I've upped my C to 3 grams a day instead of my usual 1 and my D-3 to 6,000 units instead of my usual 4,000.

[Mar 17, 2020] Here are three most helpful and competent sources

Mar 17, 2020 | www.moonofalabama.org

Dilara , Mar 17 2020 1:58 utc | 115

There are three most helpful and competent sources "How to treat Coronavirus infection COVID-19"
1. An advice from a pathologist who's been tracking the virus since 1970: United Nursing Services "Good luck for all of us"
2. The RT-Interview with the member of the Russian Academy of Science Alexander Chuchalin Translated by Scott Humor
3. Das Coronavirus-Update mit Christian Drosten | NDR.de ...
https://www.ndr.de/nachrichten/info/podcast4684.html
The German Virologie-Professor gives a lot of informations in a podcast everyday for half an hour, today was the 14th. If anybody knews the German language, it is a must to hear. He does not speak only about the medical but all the sociological problems, the media and the scientistic "fakes".

[Mar 16, 2020] One promising way to decrease chances of your infection via nose and throat this is salt water gargling and nasal rinses with the same. Also you can wear gloves when out

Mar 16, 2020 | www.moonofalabama.org

gepay , Mar 16 2020 19:03 utc | 6

The Saker has a good article - How to treat Coronavirus infection COVID-19 - by an international recognized virologist, Dr Chuchalain.

Contrary to what I have read in other articles, he says the virus does cause runny nose and sore throat along with mild fever.

The best way to deal with this is salt water gargling and nasal rinses with the same.

A method to reduce getting infected is to wear gloves when out. Handwashing is more effective than masks.

If you are infected masks do help you not infecting others. It is when the virus bypasses your immune system and infects the lower lungs that danger appears.

Then other opportunist pathogens -- pneumonia causing bacteria and fungi take up residence in the lower lungs often leading to death or lasting damage by fibrosis. Obviously it is much better to stop it before this with then no lasting effects.

If dry cough and shortness of breath appear seek medical help immediately.

[Mar 16, 2020] The US will be offering free drive-up testing to practically everyone. I now believe the United States now has a better change at containing the pandemic than Europe.

Mar 16, 2020 | www.moonofalabama.org

Petri Krohn , Mar 16 2020 19:56 utc | 28

Analyzing the swab in a lab is simple and cheap, but getting the swab to the lab is expensive. Normal testing procedures assume that the tested person is already infected. Therefore the health worker doing the swabbing will have to wear full protective clothing. Moreover, before testing the next patient he will have to disinfect and change protective clothing. One estimate put the price of a COVID-19 test in the US at $1200. Of the sum $1000 was charged for the biohazard.

In most countries testing is done only where there is a strong suspicion the person is infected with the new coronavirus. Therefore the measures against biohazards may be called for.

Testing for coronavirus must be separated from health care. People who have symptoms but do not need medical care should stay as far away from hospitals as possible. The safest and most effective way to do high-throughput testing is drive-up or drive-in testing. The patient or suspect stays inside the car and only opens a window. This way he or she does not infect others. The testing team wears full protective clothing, including a gas mask. This video by NBC News shows how it is done. A tent is set up on a huge parking lot. Hundreds of cars wait in line. The testers wear disposable aprons which they change after each suspect.

I watched VP Pence's press conference yesterday. I was actually impressed! The US will be offering free drive-up testing to practically everyone. I now believe the United States now has a better change at containing the pandemic than Europe.

The problem here and especially in countries other that the USA is that the patient needs a car. Walk-in testing is more difficult to organize as the patients need to be isolated from each other. The simplest test would be one were the test subject swabs his own mouth, puts the swab in a plastic tube and seals it in an envelope.

In the mean time Sweden has stopped testing all together, except for hospital patients. Britain and Finland have followed suit. People with symptoms are simple told to lock themselves up in their homes and not come out for two weeks. The Chinese edition of the Global Times has called the Swedes out for the surrender monkeys they are.

Containing an epidemic and avoiding a pandemic requires testing large parts of the population to locate any unknown cluster of infections. Once a case is found, the anti-corona task force must locate all contacts, test them and place them under quarantine even if they do not show symptoms.

[Mar 16, 2020] Covid-19 The Sun A Lesson From The 1918 Influenza Pandemic

Mar 16, 2020 | www.zerohedge.com

Covid-19 & The Sun: A Lesson From The 1918 Influenza Pandemic by Tyler Durden Sun, 03/15/2020 - 23:10 Authored by Richard Hobday via Medium.com,

Fresh air, sunlight and improvised face masks seemed to work a century ago; and they might help us now.

When new, virulent diseases emerge, such SARS and Covid-19, the race begins to find new vaccines and treatments for those affected. As the current crisis unfolds, governments are enforcing quarantine and isolation, and public gatherings are being discouraged. Health officials took the same approach 100 years ago, when influenza was spreading around the world. The results were mixed. But records from the 1918 pandemic suggest one technique for dealing with influenza -- little-known today -- was effective. Some hard-won experience from the greatest pandemic in recorded history could help us in the weeks and months ahead.

Influenza patients getting sunlight at the Camp Brooks emergency open-air hospital in Boston. Medical staff were not supposed to remove their masks. (National Archives)

Put simply, medics found that severely ill flu patients nursed outdoors recovered better than those treated indoors. A combination of fresh air and sunlight seems to have prevented deaths among patients; and infections among medical staff. There is scientific support for this. Research shows that outdoor air is a natural disinfectant. Fresh air can kill the flu virus and other harmful germs. Equally, sunlight is germicidal and there is now evidence it can kill the flu virus .

`Open-Air' Treatment in 1918

During the great pandemic, two of the worst places to be were military barracks and troop-ships. Overcrowding and bad ventilation put soldiers and sailors at high risk of catching influenza and the other infections that often followed it. As with the current Covid-19 outbreak, most of the victims of so-called `Spanish flu' did not die from influenza: they died of pneumonia and other complications.

When the influenza pandemic reached the East coast of the United States in 1918, the city of Boston was particularly badly hit. So the State Guard set up an emergency hospital. They took in the worst cases among sailors on ships in Boston harbour. The hospital's medical officer had noticed the most seriously ill sailors had been in badly-ventilated spaces. So he gave them as much fresh air as possible by putting them in tents. And in good weather they were taken out of their tents and put in the sun. At this time, it was common practice to put sick soldiers outdoors. Open-air therapy, as it was known, was widely used on casualties from the Western Front. And it became the treatment of choice for another common and often deadly respiratory infection of the time; tuberculosis. Patients were put outside in their beds to breathe fresh outdoor air. Or they were nursed in cross-ventilated wards with the windows open day and night. The open-air regimen remained popular until antibiotics replaced it in the 1950s.

Doctors who had first-hand experience of open-air therapy at the hospital in Boston were convinced the regimen was effective. It was adopted elsewhere. If one report is correct, it reduced deaths among hospital patients from 40 per cent to about 13 per cent. According to the Surgeon General of the Massachusetts State Guard:

`The efficacy of open air treatment has been absolutely proven, and one has only to try it to discover its value.'

Fresh Air is a Disinfectant

Patients treated outdoors were less likely to be exposed to the infectious germs that are often present in conventional hospital wards. They were breathing clean air in what must have been a largely sterile environment. We know this because, in the 1960s, Ministry of Defence scientists proved that fresh air is a natural disinfectant. Something in it, which they called the Open Air Factor, is far more harmful to airborne bacteria -- and the influenza virus -- than indoor air. They couldn't identify exactly what the Open Air Factor is. But they found it was effective both at night and during the daytime.

Their research also revealed that the Open Air Factor's disinfecting powers can be preserved in enclosures -- if ventilation rates are kept high enough. Significantly, the rates they identified are the same ones that cross-ventilated hospital wards, with high ceilings and big windows, were designed for. But by the time the scientists made their discoveries, antibiotic therapy had replaced open-air treatment. Since then the germicidal effects of fresh air have not featured in infection control, or hospital design. Yet harmful bacteria have become increasingly resistant to antibiotics.

Sunlight and Influenza Infection

Putting infected patients out in the sun may have helped because it inactivates the influenza virus. It also kills bacteria that cause lung and other infections in hospitals. During the First World War, military surgeons routinely used sunlight to heal infected wounds. They knew it was a disinfectant. What they didn't know is that one advantage of placing patients outside in the sun is they can synthesise vitamin D in their skin if sunlight is strong enough. This was not discovered until the 1920s. Low vitamin D levels are now linked to respiratory infections and may increase susceptibility to influenza . Also, our body's biological rhythms appear to influence how we resist infections. New research suggests they can alter our inflammatory response to the flu virus. As with vitamin D, at the time of the 1918 pandemic, the important part played by sunlight in synchronizing these rhythms was not known.

Face Masks Coronavirus and Flu

Surgical masks are currently in short supply in China and elsewhere. They were worn 100 years ago, during the great pandemic, to try and stop the influenza virus spreading. While surgical masks may offer some protection from infection they do not seal around the face. So they don't filter out small airborne particles. In 1918, anyone at the emergency hospital in Boston who had contact with patients had to wear an improvised face mask. This comprised five layers of gauze fitted to a wire frame which covered the nose and mouth. The frame was shaped to fit the face of the wearer and prevent the gauze filter touching the mouth and nostrils. The masks were replaced every two hours; properly sterilized and with fresh gauze put on. They were a forerunner of the N95 respirators in use in hospitals today to protect medical staff against airborne infection.

Temporary Hospitals

Staff at the hospital kept up high standards of personal and environmental hygiene. No doubt this played a big part in the relatively low rates of infection and deaths reported there. The speed with which their hospital and other temporary open-air facilities were erected to cope with the surge in pneumonia patients was another factor. Today, many countries are not prepared for a severe influenza pandemic. Their health services will be overwhelmed if there is one. Vaccines and antiviral drugs might help. Antibiotics may be effective for pneumonia and other complications. But much of the world's population will not have access to them. If another 1918 comes, or the Covid-19 crisis gets worse, history suggests it might be prudent to have tents and pre-fabricated wards ready to deal with large numbers of seriously ill cases. Plenty of fresh air and a little sunlight might help too.

[Mar 16, 2020] Scott Humor's translation of the video provided by Saker of Russian pulmonary specialist, Dr Aleksandr Chuchalin

Mar 16, 2020 | www.unz.com

Mustapha Mond , says: Show Comment March 15, 2020 at 6:28 am GMT

Scott Humor's translation of the video provided by Saker of Russian pulmonary specialist, Dr Aleksandr Chuchalin : https://thesaker.is/how-to-treat-coronavirus-infection-covid-19/

Not a very pretty read. Those who get the virus bad, and survive the pneumonia, are likely to have pretty scarred up lungs once they recover, if we can call it that. Let's hope not. But with the Han Chinese supposedly having a vastly larger ACE-2 presence in their lungs than other races, it would seem this virus is uniquely able (designed?) to cripple the Chinese long-term, via creating a vast population of people with significant pulmonary problems (pulmonary fibrosis) for the remainder of their lives, and perhaps more likely to have terrible problems requiring extensive medical care should they ever become re-infected in the future. All of which would be significant burdens on the PRC's future.

Hopefully, the Chinese government's overwhelming response to the virus will minimize this possibility.

Let's also hope this nasty bug doesn't decimate the seniors in the USA. If it does, one can already hear the MSM whipping the proles into an anti-China frenzy with, "Them damn Chinese killed your grandma and grandpa!"

And if the virus was engineered, maybe that was some pre-planned fortuitous blow-back that cuts down on the aging boomer "useless eaters" (as the supreme useless eater Dick Cheney called them), and which thereby offers enormous opportunities for world-wide anti-China propagandizing (and perhaps even a possible casus belli for the next president to mull over after the 2020 election .. )

[Mar 15, 2020] How to treat Coronavirus infection COVID-19

Mar 15, 2020 | thesaker.is

Interview with the member of the Russian Academy of Science Alexander Chuchalin

Translated by Scott Humor

Source

If a situation with the CAVID-19 coronavirus infection follows the same scenario as the SARS epidemic, then by April- May the problem will be less acute. In his interview to the RT the academic Alexander Chuchalin, the Head of Department of Hospital therapy of the Russian National Research Medical Pirogov University. In his opinion, the Russian healthcare system has done its best to protect the country from coronavirus. The doctor also says that, contrary to popular belief, infection with CAVID-19 can be accompanied by a runny nose.

Q: Not only are you one of the best pulmonologists in Europe, you are also in the main risk group now for coronavirus. Could you, please, give some recommendations for people of your generation and those who are younger, those who, as we see, are really susceptible to high mortality -- especially in China, Italy, and Iran.

A: In order to understand the risk groups for this disease: first of all, these are people who come into contact with animals that represent a biological reservoir. For example, in 2002 it was African cats, in 2012 it was camels, and now the science is a little confused, it has not been fully established. There is more evidence that this is a certain kind of bat -- the one that the Chinese eat.

This bat spreads the coronavirus through its bowel movements. After that a seeding process takes place. Let's say, it's a seafood market or some other products, and so on. But, right now we're talking about an epidemic, we are talking about people infecting people. Therefore, this phase has already arrived. The infection spreads person to person.

Coronaviruses are a very, very common viral infections, and people encounter them many, many times in their lives. Within a year a child carries diseases that we call acute colds up to ten times. And behind this acute cold are certain viruses.

And the second place in its prevalence is occupied by the coronavirus. The problem is that these seemingly harmless pathogens were dismissed, and they could never understand the cause-and-effect relationship between a common cold and a virus. If, say, a child has a cold, he has a runny nose, what will follow? And so on. For about two weeks, a child or an adult gets sick -- and all this disappears without a trace.

But in 2002, 2012, and now in 2020, the situation has changed qualitatively. Because the serotypes that have started to circulate they affect the epithelial cells.

Epithelial cells are cells that line the respiratory tract, gastrointestinal tract, and urinary system. Therefore, a person infected has pulmonary symptoms and intestinal symptoms. And in the study of urine tests, too, allocate with such a viral load.

But these new strains, which we are now talking about, they have these properties -- to come into contact with the second type of receptor, the angiotensin-converting enzyme. And this receptor is associated with such a serious manifestation as cough.

Therefore, a patient who has symptoms of damage to the lower respiratory tract, a characteristic sign is a cough. This affects the epithelial cells of the most distal parts of the respiratory tract. These breathing tubes are very small.

Q: Distal, is it distant?

A: It's far and small in diameter.

Q: So this is what we have next to the bronchi?

A: This is bronchi, then we have bronchioles, respiratory bronchioles. And when the air, the diffusion of gases goes on the surface of the alveoli, they pass just this section of the respiratory tract.

Q: That is, the primary symptom is a cough

A: No, the first is a runny nose, and a sore throat.

Q: They say that there is no runny nose.

A: No, these are big data issues. 74 thousand medical records were processed, and all of them have rhinorrhea (runny nose. – RT). When you are told this -- there are really some nuances. Biology is like this. The biological target of the virus is epithelial cells. The nose, oropharyngeal region, trachea, and then small bronchioles, targeting these regions are especially dangerous to humans. And it turned out that, having this mechanism, the virus leads to a sharp breakdown of the immune system.

Q:Why?

A: An explanation that science gives today is that a protein called interferoninduced protein-10 is involved in the process. It is with this protein that the regulation of innate immunity and acquired immunity is associated. How should we see this? As a very deep damage to lymphocytes.

Q: So you can see lymphocytes falling immediately on the general test?

A: Yes. And if there are white blood cells increase, platelets will increase, and it is more stable lymphopenia, that is, the lymphotoxic effect of the viruses themselves. Therefore, the disease itself has at least four outlined stages. The first stage is virusemia. A harmless cold, nothing special. Seven days, nine-approximately in this interval.

But starting from the ninth day to the 14th, the situation changes qualitatively, because it is during this period that viral and bacterial pneumonia is formed. After damage to epithelial cells in the anatomical space of the respiratory tract, colonization of microorganisms occurs, primarily those that inhabit the human oropharyngeal region.

Q: Do you mean bacteria that is already there?

A: Bacteria, Yes. Therefore, these pneumonias are always viral and bacterial.

Q: So the virus, so to speak, fills the alveoli, where some bacteria live all the time? And they live somewhere by themselves, in some quantity?

A: In general, we believe that the lower respiratory tract is sterile. This is how the defense mechanism works for the lower respiratory tract.

Q: There's nothing there?

A: It's not inhabited. When the virus has entered and it has broken this barrier, where there was a sterile environment in the lungs, microorganisms begin to colonize and multiply.

Q: So it's not a virus that causes pneumonia? Still, pneumonia is caused by bacteria, of course.

A: It's the association of virus-bacteria.

This is the window where the doctor must show his skill. Because often the virusemic period is like a mild disease, like a slight cold, malaise, runny nose, a slight temperature is small, subfebrile. But the period when the cough increased and when there is a shortness of breath -- these are two signs that say: stop, this is a qualitatively different patient.

If this situation is not controlled and the disease progresses, then more serious complications occur. We call it respiratory distress syndrome, shock. A person cannot breathe on their own.

Q: Pulmonary edema?

A: You see, there are a lot of different edemas of a lung. In fact, it depends on how it happens. To be precise, we call this non-cardiogenic pulmonary edema. If, say, cardiogenic pulmonary edema can be treated with certain medications, then this pulmonary edema can only be treated with a mechanical ventilation machine or advanced methods such as extracorporeal hemoxygenation.

If a person transfers to this phase, the immunosuppression caused by the defeat of the acquired and innate immunity becomes fatal and the patient is joined by such aggressive pathogens as Pseudomonas aeruginosa, fungi. And the cases of death that occurred -- 50% of those who were on artificial ventilation for a long time, the alveoli are all filled with fungi.

Fungi appear during the stage of deep immunosuppression. What is the fate of the man who endured all this? That is, he suffered virusemic period, he suffered viral-bacterial pneumonia, he suffered respiratory distress syndrome, non-cardiogenic pulmonary edema, and he suffered septic pneumonia. Will he be healthy or not? And, in fact, today the world is concerned about this: what is the fate of those 90 thousand Chinese who have suffered a coronavirus infection?

Q: But those 90 thousand -- they recovered by themselves, they weren't kept on on a ventilator, they did not get fungi. ARI or acute respiratory infection, that's it?

A: But the problem itself is very important. Because practical medicine is faced with the fact of a sharp increase in the so-called pulmonary fibrosis. And this group of people who have had a corona virus infection develops fibrosis of the lung within a year.

Q: That is, when the lung tissue thickens?

A: Yes. A lung becomes like burnt rubber, if the analogy is to be made.

Q: Say, you get an elderly person who has been accurately diagnosed with a coronavirus. And he is not yet on the ninth day, that is, he does not need to be put on a ventilator yet. How will you treat him?

A: You know what the problem is: we do not treat such patients yet, because there are no medications, medicines that should be used in this phase. There is no panacea. Because a drug that would act on virusemia, on the viral-bacterial phase, on non-cardiogenic pulmonary edema, on sepsis -- is a panacea, this drug doesn't exist.

Because if we go back to the experience of 2002, when we saw the vulnerability of medical personnel, doctors and nurses were recommended to use Tamiflu and oseltamivir -- an anti-influenza drug. And with certain serotypes of the coronavirus, indeed, the mechanism of introduction into the cell is the same as with influenza viruses. Therefore, it has been shown that these drugs can protect individuals who are at high risk of developing this disease.

Or, he is identified as a carrier of the virus, he is given these drugs and so on. But this, I want to say again, has no serious evidence base. The situation that is most threatening, because it determines the fate of a person. A cold is one thing. And another thing a viral-bacterial pneumonia, it is a fundamentally different thing.

And here it is very important to emphasize that it is problematic to help such a patient only with antibiotics. There must be a combination therapy, which includes means that stimulate the immune system. This is a very important point.

Q: What do you mean? So, relatively speaking, you will prescribe him Amoxiclav with some kind of immunomodulator?

A: Yes, we would usually prescribe fourth-generation cephalosporins, not Amoxiclav, in combination with vancomycin. This combination is broad, because very quickly there is a process of a change of gram-positive and gram-negative flora. But what immunomodulatory drug to prescribe is a question for scientific research.

So, we understand that the immune system will suffer dramatically. We understand the high vulnerability of a person to the infection that begins to colonize the respiratory tract. So, unfortunately, we don't have a clear line. But what really can help such patients in this situation is immunoglobulins. Because this is substitution therapy.

And therefore, such patients are prescribed high immunoglobulins so that they do not develop sepsis, at least they do not enter the sepsis phase. American doctors used this drug in their Ebola patient. This is a group drug, an analog of nucleosides. This is a group of drugs that are used for herpes, cytomegalovirus, and so on.

Q: So this is antiviral or antiviral-supporting therapy, right?

A: No, this is a drug that still acts on the mechanisms in the cell that resist virus replication. Here in my hands (photo of US President Donald trump. – RT). He gathered all the top people who could speak out on promising drugs. Two questions that he raised, he was preparing for this conference. The first question is: how ready are scientists in the United States of America to introduce the vaccine?

Q: Eighteen months.

A: Yes, absolutely. That's two years. He asked what in this case? Does the country have drugs that could protect? And, as a matter of fact, they said: Yes, there is such a drug.

Q: What?

A:What kind of drug is this? It's called Remdesivir

Q: Let's look at it.

A: That's what scientists said, given the experience that we have, and discussions and so on. Although, of course, there are other drugs that are being actively studied. In general, this direction is very interesting: in fact, it is considered promising. The use of mesenchymal stem cells is considered promising. But at what stage?

Q: As a person who has been doing this for many years, treating everything from asthma to pneumonia, can you somehow try to predict the development of this epidemic, for example, in Russia?

A: I want to say that if we compare Russia with the surrounding world in case of the coronavirus of 2002. We didn't have a single patient here.

Q: Maybe we just didn't diagnose them?

A: As you know, there are strong aspects of Russian healthcare in this situation, and I would like to stress this. This is the work of our sanitary and epidemiologic services. They really did their best to protect our country. This is on one side, as if punitive measures. And on the second side is the work of the Vector Research Institute, which made diagnostics for the coronavirus in a very short time, and they did everything absolutely. And it was tested at the CDC, and they got a certificate indicating high specificity and sensitivity.

Q: The Vector diagnostic kit is the only certified

A: Yes.

Q: The virus is already in Russia, no matter how much the sanitary service tries. How do you think it will develop? Will it end in the spring, for example, with the arrival of summer?

A: You know, I think the picture repeats what it was then with the SARS. If you remember

Q: Then? Do you mean in 2002? When it was SARS?

A: Yes, that's the one. If we follow this scenario, we should say that somewhere in April or May this problem will become less acute.

Q: Just because of the seasonal cessation of respiratory infections?

A: Yeah. The climate factor and a number of other factors. Now, the trouble, of course, comes to us not from China, but from Europe. Those who return from these countries, primarily from Italy, today, remember: Carlo Urbani . He accomplished a lot of things. I think this is just a hero of a doctor who has done so much. He was a virologist from Milan.

Q: Back in 2002?

A: He was a WHO expert. I met with him through the World Health Organization. He was on the list as an expert on coronaviruses. And then he was sent to Hanoi. They were dispatching doctors, and he got to go to Vietnam. And in Vietnam, when he arrived, there was a panic. Their doctors stopped coming to work. Their medical staff, also. There had patients, but there wasn't any medical personnel and no doctors.

He assessed the situation. With difficulty, he managed to break it, to remove this panic situation that was then in the hospital. But most importantly, he began to communicate with the government and said: close the country to quarantine. That's where it all came from. It came from Urbani. They started to fight back.

Q: The Vietnamese?

A: Yes, the government of Vietnam. That this would affect the economy, tourism, and so on. But, he found these words, he convinced them. And Vietnam was the first country to come out of this. And he thought his work was done. He collected material for a virological examination and boarded a plane to Bangkok.

He was supposed to meet with the American virologists there. During the flight, he realized that he got ill. He got sick, just like those poor Vietnamese in that hospital. And he began to write everything down and describing it. This is this exact time, and this is how I feel.

Q: The flight was about three hours?

A: Yes, about three hours. And during these three hours, he became an invalid who couldn't get up and move on his own. Here we see how the window itself works, and we understand when pneumonia joins -- this window can be extremely, extremely short in duration. And when he was barely able to get down the aircraft ladder, he left the last entry: "I'm waving to them so they don't come near me."

That is, American virologists wanted to meet Urbani, but he said: let's not contact. He died in an intensive care unit. And there was an autopsy. And from his lung tissue was isolated a strain that was named after him – "Urban I-2". Here is a very story that I am telling you. A tragedy, of course.

Q: What would you recommend to a person who finds himself Well, we have already agreed that the virus is in the general population. We can't really control it anymore.

A: Are you asking for some simple recommendations? First of all, take a good care for the nasal mucosa and oropharyngeal area.

Q: To wash it with saltwater?

A: Yes, wash it thoroughly. But "lors" – non-prescription medications and sinus cleaners to stop running nose and for an effective lavage. That is, the feeling of free unobstructed breath should come after all. The second thing is the oropharyngeal area behind the uvula. And there, too, you need to make a good lavage of the oropharyngeal region.

Q: So you don't just have to squirt it up your nose, you have to gargle it deep down your throat?

A: Yes, and rinse it out. And don't be lazy. Do do it until you get a feeling of clean, good airways. Of all the ways, this is the most effective. I would advise those people who can afford to buy a nebulizer or

Q: Do you mean, it's aerosol, right? With ultrasound?

A: Yes. And it allows the hygiene of the upper respiratory tract to be brought to a good state. When a cough starts, it is desirable to still apply the medications that we prescribe for patients with bronchial asthma. This is either Berodual, or Ventolin, or Salbutamol. Because these drugs improve mucociliary clearance, relieve spasm.

Q: You mean expectorant?" Mucolytic ACC?

A: Yes, ACC and Fluimucil. And what you can't do is use glucocorticosteroids. This virus replication is rapidly increasing by them.

Q: What does that mean?

A: Corticosteroids is prednisone, methylprednisolone, dexamethasone, betamethasone.

Q: So you don't need to inject hormones, relatively speaking, if you have a viral infection?

A: There are inhaled steroids. But there are patients with asthma who are ill and are on this therapy. But this has to be a tailor-made solutions. Of course, 2020 will go down in medical history as a year of a new disease. We must admit that we have understood this new disease. Two new pneumonias have arrived. First is pneumonia, which is caused by e-cigarettes, vapes, and now in the United States, people have died from this

Q: several thousand teenagers. Yes, this is a well-known fact, and how to treat it is unclear. You put them on a ventilator -- they die immediately.

A: Yes. Do you understand what the problem is? Here they develop those changes in the lungs that occur during this process. They seem to be similar (to the changes from the coronavirus). This is respiratory distress syndrome, which we are talking about. The literature raises very serious questions: the role of coronaviruses in transplantation. One of the problems is obliterating bronchiolitis, which occurs especially during transplantation.

Q: A lung transplant?

A: Yes, lungs and bone marrow. Stem cell. As a matter of fact, everything is well done, everything is normal, the person has responded to this therapy, and the problem of respiratory failure is beginning to grow. And the cause of these bronchiolitis was caught -- it is a coronavirus That is, new knowledge has come.

How to treat Coronavirus infection COVID-19 in Russian

https://www.youtube.com/embed/FbRJLcRBSOY?feature=oembed

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48 Comments

Larchmonter445 on March 14, 2020 , · at 11:05 pm EST/EDT

Scary as hell.

What a biological horror.

They want everyone to socially distance themselves. Just read this interview.

Scott on March 14, 2020 , · at 11:15 pm EST/EDT
I had SARS back then. My regular dentist called sick, and his partner just came from Vietnam.
I was ill bedridden for 6 weeks with a viral pneumonia. Refused to be hospitalized, though.
Socializing was the last thing on my mind.
Harry_Red on March 15, 2020 , · at 5:10 am EST/EDT
I can attest from experience that a mixture of salt and warm water is the number one remedie in the arsenal against these types of infections.

Use it aggressively !

Two to three teaspoons of salt in a glass mixed with warm water. Try to gargle it in small to medium sips for about 5 minutes. You might not finish the entire glass in 1 sitting. Save the glass.

Repeat this process every 2 to 3 hours. It is one of God's miracles ;-) .

Besides viral infections, you can even cleanse your teeth and gums regularly with salt water.

Another important remedie for soar throats is squeezing half a lemon and mixing it with the highest quality honey available to you, without diluting the mix in water. Let it burn your throat, if it does, it will eventually have a soothing feeling after repeated sips and repeating sittings.

May God keep you all in good health !

Anonius on March 15, 2020 , · at 11:03 am EST/EDT
Funny, this is what my mother's family always used. Salt and water is also very effective on swellings and bruising.
Babushka in Oz on March 14, 2020 , · at 11:30 pm EST/EDT
Thanks Saker and Scott a very timely translation.

Regarding the treatment steps, the following relates to asthma, but may be of interest

The National Asthma Council Australia video on how to perform nasal irrigation.

https://www.nationalasthma.org.au/living-with-asthma/how-to-videos/how-to-perform-nasal-irrigation-with-fess-sinu-cleanse

Maiden PEI on March 15, 2020 , · at 12:41 am EST/EDT
I CAN TESTIFY TO THE GREAT EFFECTIVENESS OF NASAL RINSES

If I start nasal rinses as soon as I feel the throat tickle of a cold coming on, I don't get the cold.

I haven't had one in years.

This year, though, I mustn't had started the rinses soon enough as I did get the cold.

BUT, instead of stopping the rinses, I upped them to every 2hrs & I never had to blow my nose ONCE all through the two week cold!

AND it wasn't miserable, like usual, at all.

I gradually decreased the frequency of the rinses as the cold got better.

I was continuing the rinses, preventatively, every day, but now with the added risk of COVID-19, I will increase that to AM & PM, as recommended &, of course, will increase that if I become symptomatic.

Babushka in Oz on March 15, 2020 , · at 2:37 am EST/EDT
As a former yoga teacher I can also recommend Alternate Nostril breathing.

To clean the sinus, clear the head and calm the mind and spirit. Super essential now to supercharge our bodies with positive energy and clear the lungs.

I have the advantage of living near a beach and this is part of my daily walk and deep breathing ritual. I have not had a cold or sniffle for a many years, nor do I ever have the flu injection.

https://www.healthline.com/health/alternate-nostril-breathing

Pamela on March 15, 2020 , · at 2:08 pm EST/EDT
I recently learned of this too Babushka. It's helpful for learning how blocked – often from internal swelling due to inflammation – they can be. Breathing with both, we learn to interpret the compensation, so we can easily think "Oh I dont have a problem. This can be wrong, as I discovered I was.. When I tried to alternate nasal breathe, I was shocked at how I almost couldnt. Breathe, that is. It was an eye opener for me.

I had been suffering from internal nasal swelling due to my reaction to Salicylates – which I'm among those people intolerant of. I've had it since childhood but just let it go, eating the fruits I love so much. But on realising how bad the nasal results were, I got checked for polyps and then just cut the food out.

I also learned the saline nasal washes from the Indian nurses and Doctors I made friends with years ago in UK. You dont need a machine – as I'm sure you know. They just pour normal saline** into a cupped palm of hand, close off the opposite side nasal with opposite hand, and slowly inhale it to reach the back of the nasal passage, then repeat changing sides.

** N/Saline is roughly 1 tsp salt in 1L water!!

Glad to see you are staying well. Are you as glad as I you dont live in UK, now that we'd be condemned to isolation for 4 months
And then some wonder why I keep saying – the reaction is out of all proportion to the infection!!

Babushka in Oz on March 15, 2020 , · at 6:03 pm EST/EDT
Thanks Pamela

Yes, keeping as well as possible as the insanity descends on this great land.

My husband is a great believer in cold water swimming to keep the immune system in good tune – does it all year round – every day ritual. Not my thing, but turning the shower to cold for the last few bursts will also close the pores and boost immunity.

Btw – I am a different person to Babuška, who also lives in Aussie and shares her wonderful wisdom in the cafe.

S75ponny on March 14, 2020 , · at 11:58 pm EST/EDT
Many thanks to Alexander Chuchalin for sharing his expertise and also to Scott Humor for this translation.

Abundance of information which I was waiting for.

TEP on March 15, 2020 , · at 12:03 am EST/EDT
Excellent informative article. This should be shared extensively in the current COVID-19 environment, particularly among healthcare professionals.
S75ponny on March 15, 2020 , · at 12:50 am EST/EDT
"This should be shared extensively in the current COVID-19 environment, particularly among healthcare professionals."

Done already at fairly high level, so far no applause. Let's give them time to digest and overcome their sense of innocent supremacy

Just saying

Jim Dukarm on March 15, 2020 , · at 12:07 am EST/EDT
Scott, молодец.
Oliver K on March 15, 2020 , · at 2:23 am EST/EDT
I do not understand the general recommendations:

"A: Are you asking for some simple recommendations? First of all, take a good care for the nasal mucosa and oropharyngeal area.
Q: To wash it with saltwater?
A: Yes, wash it thoroughly. But "lors" – non-prescription medications and sinus cleaners to stop running nose and for an effective lavage. That is, the feeling of free unobstructed breath should come after all. The second thing is the oropharyngeal area behind the uvula. And there, too, you need to make a good lavage of the oropharyngeal region.
Q: So you don't just have to squirt it up your nose, you have to gargle it deep down your throat?
A: Yes, and rinse it out. And don't be lazy. Do do it until you get a feeling of clean, good airways. Of all the ways, this is the most effective. I would advise those people who can afford to buy a nebulizer or
Q: Do you mean, it's aerosol, right? With ultrasound?
A: Yes. And it allows the hygiene of the upper respiratory tract to be brought to a good state. When a cough starts, it is desirable to still apply the medications that we prescribe for patients with bronchial asthma. This is either Berodual, or Ventolin, or Salbutamol. Because these drugs improve mucociliary clearance, relieve spasm."

1. Okay, the "washing with sea water" I associate with the sea water nasal sprays -- is this roughly correct?
2. But what is meant with "lavage"? Gurgling with salt water, say?
3. And then the aerosol thing, what is that? Is this related to the good old method of putting hot water with something into a bowl, your head over it, and cover with a towel?

Maiden PEI on March 15, 2020 , · at 4:13 am EST/EDT
WASHING WITH SEA WATER – he is talking about what is called "nasal rinses" also called "nasal washes" or "nasal lavages" look online for videos how to do it.

LAVAGE – is French for "wash", here he means "nasal washes" not gurgling.

BOTH nasal washes & gurgling (back of throat) should be done for regular/usual nose & mouth hygiene, to prevent colds/flu & to relieve cold/flu symptoms.

AEROSOL – no, not putting head over hot water, that's "steam inhalation" aerosol is a fine mist, either sprayed or inhaled from a device, like for asthma.

Hope this explanation helps!

Oliver K on March 15, 2020 , · at 5:16 am EST/EDT
Thanks.
I understand now the "nasal washes" part: found
https://en.wikipedia.org/wiki/Nasal_irrigation
Wikipedia Nasal irrigation
and also found (simple) devices which one can purchase. That solves that.

But the "gurgling" is still unclear to me. The text sound as if it weren't just ordinary gurgling, but part of the nasal irrigation, somehow.

Concerning the mist to be inhaled: in recent weeks I was searching for information and devices about that, but couldn't find much solid information for the simple uses related to colds. So I opted for buying a simple small device which boils water, and one puts some essential oils in it. This steam inhalation is traditional, easy to understand, and one feels the effect.
Found
https://en.wikipedia.org/wiki/Nebulizer
Wikipedia Nebulizer
but that also doesn't speak about the non-medical use. One can buy devices, but information is always about the medical cases. So for now I stay away from that.

Just an ordinary pleb on March 15, 2020 , · at 9:48 am EST/EDT
He means "Gargling" I believe. Sage tea was a common gargle for sore throats etc in the past.
Oliver K on March 15, 2020 , · at 10:19 am EST/EDT
Indeed, I meant "gargling".
For some time I used in the UK the word "gurgling" when I mean "gargling" -- people would then always "gurgle", but never say something (I guess they thought I wanted to be funny ;-)).
Anonius on March 15, 2020 , · at 11:07 am EST/EDT
Not so fast, water heavy on salt is excellent for gargling your sore throat. Centuries old method. Of course other natural methods work also.
Michel V. on March 15, 2020 , · at 4:42 pm EST/EDT
Hi, you can also use a "nebulizer" to nebulize essential oils without water as a carrier: the essential oils will have an easy way to go deep into the respiratory system. (I would use all kind of soft essential oils and in some case add a little bit of strong oils).
I made some French and Dutch pages about this, here is a link to an avi, showing the working of such a nebulizer. Not to confound with the fancy products that use water as a carrier!
No spam intended as I have not enough to sell here anyway I'm in France and we are almost in complete lockdown anyway now: to moderators)

http://www.cevenat.fr/wp-content/uploads/2020/02/diffuseur.avi

You also have ventillators that "diffuse" essential oils through a pad, less effective than the "real nebulizers", but still effectif in hospitals:
Voir aussi :
Voici deux liens (anciens), de l'utilisation de diffuseurs dans l'hôpital de Manchester au Royaume-Uni:

http://news.bbc.co.uk/2/hi/health/4116053.stm
Article de 2004, dans le contexte des maladies nosocomiales.

Le lien suivant, de l'hôpital de Wytenshawe montre un appareil par ventilation plus grand:
http://news.bbc.co.uk/2/hi/uk_news/england/manchester/6471475.stm

Un autre lien relaté sur la puissance des huiles essentielles.
http://news.bbc.co.uk/2/hi/uk_news/england/sussex/8584753.stm

Staph Infection ressources:
https://www.staph-infection-resources.com/prevention/airborne/

Daniel on March 15, 2020 , · at 3:44 am EST/EDT
The Saker

The Russian Academic is a smart fellow, but I think following the money can yield results quicker and easier. Covid-19 may be a new virus, but the script is old and worn out from overuse. I personally got acquainted with this bloody script during the aids pandemic. The script albeit macabre, is simple and makes good business sense. Recurring expenditure by patients makes for guaranteed income for big "Pharma". Hence the cure for almost all diseases is permanent medication for the patient. This is called "Corporate Interests" and Doctors, Academics, politicians, me and you are under its complete domination. Summer is coming to the Northern hemisphere and with it come the reprieve from the pandemic, but please keep your focus on the money for that's were they will reveal themselves.

Saji Hameed on March 15, 2020 , · at 4:56 am EST/EDT
I am much inclined to agree with Daniel.

I was a bit confused by the Russian academician's assertion that the lower respiratory tract (lungs etc.) are not inhabited by bacteria. This is not true https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297685/ Therefore, some of the assertions by the good physician might be incorrect to some degree.

What is known for sure is that a huge scare campaign is going on among the world's media, and governments are forced to do things that may not be in the states' best interests. Accompanying this is a distinct lack of objective information related to the disease and the virus responsible for it.

I hope the discourse turns sane soon; in a large sense, the impact of the virus has been negligible considering that it has been out there at least for 3 months at the end of the winter season.

I too look forward to understand who will profit from this scare.

Lumi on March 15, 2020 , · at 8:18 am EST/EDT
Yes Daniel, yes Saji, I happily agree with you. Let's not succumb to fear. Thanks Harry for the salt water reminder. Thanks translators for this informative Interview.
Makedonia on March 15, 2020 , · at 5:38 am EST/EDT
I must say that I am quite disappointed with both Russia and China in that they are more or less following or copying the Western model of conventional medicine and it seems either the medical professional there are either just looking at how to make as much money as possible from human suffering or it's just more "modern" to adopt the Western way of doing things. The Chinese themselves are abandoning 5000 years of proven traditional medicine that has shown effectiveness in dealing with almost all disease as well as successfully fighting various plagues that have attacked their country over the centuries. As is the case, Chinese now want to look modern and use Western pharmaceuticals. It's a massive shame that Russia and China don't get together and create a new model of medicine incorporating both traditional and modern scientific means. They both have the resources, knowledge and ability to do so. People don't even realize the miraculous innovations that Soviet doctors accomplished but have been lost along with other feats of that era. Western medicine or Big Pharma preys on people's suffering for the sake of profit. Even Goldman Sachs admitted there is no profit in the cure of cancer.
Anyway, in regard to the current situation, what I do is follow Dr Andrew Saul's protocol to fight the virus. It involves cheap and effective vitamins including vitamins C and D3, selenium, zinc and magnesium. Vitamin C is so so important. Even Chinese doctors are now using it in their fight against the virus. Also I take elderberry, medicinal mushrooms, olive leaf and other antiviral supplements. I urge you to do an internet search on these and in particular Andrew Saul's protocol. Additionally, I do a lot of things to strengthen my immune system like taking infra-red saunas. And if I needed treatment I would consider ozone therapy and hyperthermia to kill the virus. Listen to podcasts by Gary Null, Mike Adams of Natural News, Dr Ronald Hoffman of Intelligent Medicine, and a great interviewer on http://www.extremehealthradio.com . These guys are a treasure trove of information and who I consider the real American heroes.
I write this because it's not intended to replace professional medical advice but is only what I do and what I would do regarding both the coronavirus and good health in general.
But in the end, the current medical system based on greed and profit must be replaced or we will forever see loved ones needlessly suffer and die.
Blue Dotterel on March 15, 2020 , · at 5:43 am EST/EDT
Thanks for the translation Scott,

An article in Zero Hedge also addresses this issue in a slightly different way:
https://www.zerohedge.com/geopolitical/tverberg-it-easy-overdo-covid-19-quarantines

The conclusion is one that I would advocate based on my life experience:

"We also need to be looking for new approaches for fighting COVID-19. One approach that is not being used significantly to date is trying to strengthen people's own immune systems. Such an approach might help people's own immune system to fight off the disease, thereby lowering death rates. Nutrition experts recommend supplementing diets with Vitamins A, C, E, antioxidants and selenium. Other experts say zinc, Vitamin D and elderberry may be helpful. Staying away from cold temperatures also seems to be important. Drinking plenty of water after coming down with the disease may be beneficial as well. If we can help people's own bodies fight the disease, the burden on the medical system will be lower."

I have rarely suffered from the "flu", maybe 3 or 4 times in my 60+ years, and rarely suffer from colds (usually ending within 3-4 days). When I do suffer from the latter, it is usually as a result of improper dress for inclement weather, or a week of inadequate eating; that is, not usually eating a well balanced diet, as I usually strive to do.

So instead of accentuating the negative, maybe, we should consider strengthening the positive things we can do. Of course, the aged and infirm need to be dealt with otherwise. But the key for the rest of us is strengthening our immune systems.

Opport Knocks on March 15, 2020 , · at 6:39 am EST/EDT
In my experience, the best preventative is an alkaline diet as viruses need a human blood environment that is slightly more acidic than the normal 7.35 to 7.45 range in order to propagate. I have been 5 years cold/flu free.

If you start to experience symptoms, one trick to quickly elevate blood pH is to sleep with a piece of sliced onion (yellow are best) in your socks. The sulfides in the onions will elevate blood pH and by morning the symptoms are gone.

https://www.mynaturaltreatment.com/natural-ways-to-prevent-coronavirus-covid-19-infection

Daniel on March 15, 2020 , · at 7:51 am EST/EDT
Following the Scientific way to understand an economic stunt like Covid-19 is time wasting. Big "Pharma" will come with a solution and it is called lifetime medication (jokingly called 'three times a day). During the Aids epidemic, I did a lot of research on Virology and Toxicology in order to understand certain logic defying things regarding the epidemic progression. All I could come up with is that medicine has long parted ways with objective scientific practice under immense pressure from Big Pharma. People it doesn't pay to cure a disease but it is highly profitable to come with a so called "life prolonging substance" (aka Patenting).. Unfortunately during this phase of instilling mortal terror in the masses, a lot of innocent lives will be lost during the winter season. Things will clear up in summer and by then more information will be available and patterns would be clearly discernible.
Robert Shule on March 15, 2020 , · at 4:20 pm EST/EDT
I wonder if the Covid-19 pandemic will subside when the MSM ratings begin to decline because people will be getting tired of the regurgitated news, and a new news story will come up?

By the way, Russian Doctor gives very sensible advice. This is the kind of information we should be getting on the MSM, but are not.

metamars on March 15, 2020 , · at 10:17 am EST/EDT
I'm not a doctor, but I thought this information was so important, I immediately alerted my doctor. I encourage everyone else to do so, also. Most of it, we can't actualize, directly. However, the information about lavage could be life saving, and I haven't heard that ANYWHERE else, certainly not in official pronouncements or mainstream media. (With one exception, viz. Dr. Oz, I haven't even heard about people boosting their Vitamin D levels. This, in spite of research showing that going from Vitamin D deficiency to sufficient supplementation can cut your risk of upper respiratory infection in half.)

I am wondering why this doctor did not mention Vitamin D, either. Yes, it's of limited usefulness after an infection already sets in, but, at least in the US, we are looking at the medical system getting overwhelmed. Some people put Vitamin D deficiency levels in the US at 40%. If we can cut the risk of needing a ventilator in half, for 40% of the population, that might flatten the curve enough to avoid forcing doctors to cut off treatment to people over a certain age. (I have read that this is being done in Italy, though I don't know, for sure.)

Note to commentator: moderation policy is no use of caps .. caps have been removed mod

teranam13 on March 15, 2020 , · at 10:55 am EST/EDT
Scott, a million thanks. Now you are talking my language. I'm e mailing this to all my friends especially the ones in the medical field.

I'd like to know more about the Vector disposal kits, however. Will research it.

teranam13 on March 15, 2020 , · at 11:36 am EST/EDT
From Mike Adams at Naturalnews.com

put in an essential oil diffuser or a deep lung nebulizer

3% hydrogen peroxide ( phew! is really strong, go easy)
2 drops of iodine
colloidal silver ( my little generator makes 12ppm)

Probably the total liquid amount will be 50cc or 1/8 cup? depending on the capacity of your device. Usually respiratory treatments are from 10-15 minutes. My guess would be to mix the colloidal silver 2:1 as a liquid base. Colloidal silver is touted to interfere with viral wall and its replication abilities.

PeterP on March 15, 2020 , · at 11:51 am EST/EDT
Vaping for the 65+ ..1 tablespoon of Vick's dissolved in a quart of boiling water, breath in deeply repeatedly.
V on March 15, 2020 , · at 12:12 pm EST/EDT
Thank you so much Scott for translating this important information – I am going to email to family and friends. Also going to stock up on more salt. Already do the Vit D.

Funnily enough my mother said to me back in early February that gargling and cleansing with salt water was the best thing to use to avoid the Covid 19 virus she was so right!

Why aren't our governments, health services and media telling us to do this? Such a simple thing that everyone can afford to do ..I think we all know .

Craig Mouldey on March 15, 2020 , · at 12:32 pm EST/EDT
Well, this is not 'just a cold'. It is much worse. This finally would explain the extraordinary measures taken worldwide to try and contain it.
And I'm 66.
Col...'the farmer from NZ' on March 15, 2020 , · at 5:14 pm EST/EDT
Yeah Craig, that idiotic brigade has so much egg on their faces now they will be looking like fried omelets!
I'm 66 this September too.

Take great care
Col

Craig Mouldey on March 15, 2020 , · at 12:49 pm EST/EDT
It was rather eye-opening with his remarks that if someone contracts Corona virus within a year changes occur to the lungs. A thickening.
California on March 15, 2020 , · at 1:10 pm EST/EDT
Birdseed. The Russians seem to have left a clue. One should ask what the number is of this useful protein. If it is Nsp15 it is in my exotic birds' mix. I ordered 8 pounds of the specific seed which were delivered last Thursday and will order another batch when possible. If the virus doesn't get me, my husband will. I am no scientist but there are some coincidences here.

Favorov explains that the virus mimics a useful protein consumed by human cells. It seems that the cells of an older organism require this "useful" substance in much larger quantities and thus fuse with the virus more actively.
https://www.rt.com/news/482612-coronavirus-specialists-odds-catching-surviving/

I knew researchers were homing in on Nsp15 and this is what gets interesting. Virology gives the role of Nsp15 in coronavirus replication as enigmatic. When I read virology I thought-weird- Nsp15 is acting like two different proteins. Then I saw Favorov's explanation, the real protein and an imposter protein. "EndoU-deficient coronaviruses were viable and replicated to near wild-type virus levels in fibroblast cells." This would explain why the elderly are hit hardest.

Tuesday, March 3, 2020 2:19PM
RIVERSIDE (KABC) -- A team that includes UC Riverside researchers has identified a protein in a virus from the previous decade that might prove beneficial in developing a vaccine to combat novel coronavirus, according to the university.

Researchers isolated a protein designated, designated as "Nsp15," from the severe acute respiratory syndrome – SARS – outbreak of 2003 that could be useful in testing for vaccines intended to prevent or reduce the threat of coronavirus, also known as COVID-19. The protein found in coronavirus is 89% identical to a protein discovered in SARS, suggesting that drugs developed to treat that disease could work for the current outbreak plaguing countries around the world.

Virology. 2018 Apr;517:157-163. doi: 10.1016/j.virol.2017.12.024.
EpuCoronavirus EndoU is encoded within the sequence of nonstructural
protein (nsp) 15, which was initially identified as a component of the
viral replication complex. Biochemical and structural studies revealed
the enzymatic nature of nsp15/EndoU, which was postulated to be
essential for the unique replication cycle of viruses in the order
Nidovirales. However, the role of nsp15 in coronavirus replication was
enigmatic as EndoU-deficient coronaviruses were viable and replicated
to near wild-type virus levels in fibroblast cells. A breakthrough in
our understanding of the role of EndoU was revealed in recent studies,
which showed that EndoU mediates the evasion of viral double-stranded
RNA recognition by host sensors in macrophages. This new discovery of
nsp15/EndoU function leads to new opportunities for investigating how
a viral EndoU contributes to pathogenesis and exploiting this enzyme
for therapeutics and vaccine design against pathogenic coronaviruses.

teranam13 on March 15, 2020 , · at 1:42 pm EST/EDT
immunolgy is not my forte but this article discusses how testing is done..
It is a bit academic but the concepts are there.

https://www.creative-diagnostics.com/Immunochromatography-guide.htm

and this further explains the concept and why it is handy in the field

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268275/

Col...'the farmer from NZ' on March 15, 2020 , · at 1:55 pm EST/EDT
Interesting .Not so much as a murmur yet from the idiotic "its just a cold" brigade.
KINZAZA on March 15, 2020 , · at 4:04 pm EST/EDT
PLANdemic is a new word that is becoming very popular. Here is a nice overview of the medical marshal law, and how it all came about. Very detailed and superbly researched. https://www.youtube.com/watch?v=xW2oHhN3heo

Saw lots of military today in my area, and yet I feel like there is something isn't working for the insects who self-elected themselves to rule over humanity. The theater curtains are full of holes, and too many people can see the genocidal actors and their pathetic scripts.

Ishkabibble on March 15, 2020 , · at 5:05 pm EST/EDT
Assuming that I French kiss a person who has covid, how much time from the moment that kiss is ended, if any, do I have to wash away "all traces" of that kiss from my mouth in order to prevent being infected with covid? A. Impossible to prevent infection. B. Mere seconds. C. A few minutes. D. An hour. E. 24 hours.

Assuming that I "catch" covid from an infected person TODAY, in exactly how much time will the most sensitive test available report/confirm that I am indeed infected with covid? A. An hour. B. 24 hours. C. 48 hours. D. 72 hours. E. 7 days. F. 14 days. G. 30 days? What is the market name for the most sensitive test available for earliest possible detection? How do the 15-minute, Chinese-developed blood tests stack up against the most sensitive?

Assuming that I "catch" the covid infection today, in exactly how much time will/can the covid in ME be transmitted to others? For example, if I sneeze into the air tomorrow and someone inhales some of those droplets, will those droplets "infect" that person with covid? If not tomorrow, how many days down the road?

Thanks.

Col...'the farmer from NZ' on March 15, 2020 , · at 5:09 pm EST/EDT
Money, Money, Money Trump language yet another example of obscene unveiled greed it will not go down well with the Germans.
A quote from the below link

"According to an anonymous source quoted in the newspaper, Trump was doing everything to secure a vaccine against the coronavirus for the US, "but for the US only".

The German government was reportedly offering its own financial incentives for the vaccine to stay in the country.

The German health minister Jens Spahn said that a takeover of the CureVac company by the Trump administration was "off the table". CureVac would only develop vaccine "for the whole world", Spahn said, "not for individual countries".

https://www.theguardian.com/us-news/2020/mar/15/trump-offers-large-sums-for-exclusive-access-to-coronavirus-vaccine

PokeTheTruth on March 15, 2020 , · at 5:10 pm EST/EDT
Excellent article, thank you Saker and Scott for the translation. I have five questions.

1. Can a person be infected with influenza and coronavirus at the same time? I ask because there is an epidemic of influenza in the U.S. with 29,000,000 (29 million) so far and the symptoms are nearly the same between them (e.g., coughing, sneezing, body chill, muscle ache, intestinal disorder, fever.)

Source: https://www.contagionlive.com/news/us-flu-cases-reach-29-million-have-we-hit-peak-season

2. We read of the horrific numbers coming out of Italy. Are there different strains of coronavirus active, some being more virulent than others? Can those different strains be identified by microscopic examination?

3. Did Dr. Chuchalin have an opinion as to whether this epidemic of coronavirus was developed in a laboratory as oppose to in nature?

4. Did Dr. Chuchalin have an opinion about more than one "patient zero" originating from geographic locations other than from Wuhan, China?

5. Vaccines such as for influenza introduce antigens to stimulate the immune system and create antibodies to neutralize that particular strain of the virus. Every year a vaccine is created to address new strains of the flu. However if a person does not receive the yearly vaccine (like me), the body will fight off the infection and once an antibody has been produced, a copy remains in the body so that if the same antigen appears again, it can be dealt with more quickly.

Source: https://www.medicalnewstoday.com/articles/320101#immunity

My question: If a person contracts cononavirus and successfully recovers through normal palliative care, does he/she now have immunity to that strain of coronavirus like what happens with influenza?

Milan on March 15, 2020 , · at 6:28 pm EST/EDT
Warning here about nasal rinses. My Doctor was adamant never ever use regular water it is extremely dangerous. The water has to be sterile which means buy distilled water otherwise you are playing a very dangerous game one that will kill you.

Be healthy and safe.

teranam13 on March 15, 2020 , · at 7:06 pm EST/EDT
The question was posed can one have two viral infections at the same time? Since in the USA the medical incompetents did not test, no one knows what they have when they exhibit symptoms unless the person becomes critical.

The first testing in the USA took 24-72 hours because the Feds forbade the state labs from testing so samples had to be sent to the CDC in Atlanta. Lab testing takes awhile.

Now in the above article Mr.Chuchalin mentions Vector diagnostic kits–with this one can get a result in 10 minutes and the amount of training necessary to administer and read it is minimal. 10 freaking minutes!!!!

So all I can tell you is my experience here at ground zero in Roseville, CA which hosted the first fatality ( at least the first diagnosed one). I had the usual flu which I contained after 10 days. Then I had to have some very needed dental surgery ( two hours worth) after which strangely enough I contracted an unusual rhinitis–watery flow from my nose and into the back of my throat. I never get this. Then there came a dry cough and an ache in my upper chest. ( no temperature and no shortness of breath). I am on antibiotics for the dental surgery so that actually is good. ( old school ampicillin). So now I have a stint of staying in, gargling to prevent migration deep into the lungs. , giving myself breathing treatments with colloidal silver, taking all sorts of anti viral herbal medicines to cut viral reproduction etc. Thanks to the above article I was able to focus in on what was possibly going on and rather than continue to be puzzled by it or ignore it, I am on it!!!

So, in my opinion,,,yes, one can have two viral infections at once or one after another.

Azorka1861 on March 15, 2020 , · at 8:05 pm EST/EDT
2019–20 coronavirus pandemic by country and territory and Template

2019–20 coronavirus pandemic data / WHO situation reports on March 15, 2020

https://en.wikipedia.org/wiki/2019%E2%80%9320_coronavirus_pandemic

Jim on March 15, 2020 , · at 8:47 pm EST/EDT
Scary stuff yet surely a vital statistic is missing. These people must have a clear understanding of the mortality rate associated with this infection. They are locking down the entire world so it seems likely they would have looked into this a little bit.

The number of celebrities contracting the disease seems to be flatlining possibly because this phenomenon strongly advertisers a widespread contamination. If such large scale contamination exists in the populace it follows that the mortality rate is far lower than stated.

Anyway stock markets have crashed but only so far. They are predicting the end of the economic system as we know it. Someone somewhere does not believe them.

JC on March 15, 2020 , · at 8:52 pm EST/EDT
Life saver: Stabilized allicin extracted from garlic (Allimax/AllicinMax). This is such strong medicin to all kinds of infections that first time users should be aware of the possibility of herxheimer reactions if more than the recommended amount of capsules are taken.

My brother-in-law suffered from Lyme disease in the brain where it is very hard to get rid of because of the blood-brain barrier. No medication did him any good until he started taking AllicinMax capsules that cured him completely.

In case of infection of the lungs allicin in a sterile solution can be inhaled with the help of a nebulizer. No kidding, 100% corona proof!

More info here:
US: https://www.allimax.us/
CA: https://allimax.ca/
UK: https://www.allicin.co.uk/
DE: https://www.allicin-allimax-deutschland.de/

Stay healthy!

[Mar 15, 2020] French Health Minister Warns Certain Drugs May Aggravate Coronavirus Infection

Mar 15, 2020 | sputniknews.com

French Health Minister Olivier Veran, a qualified doctor and neurologist, on Saturday warned of certain types of anti-inflammatory drugs that may worsen the infection and the spread of the coronavirus.

"The taking of anti-inflammatories (ibuprofen, cortisone ) could be a factor in aggravating the infection. In case of fever, take paracetamol. If you are already taking anti-inflammatory drugs, ask your doctor's advice," Veran tweeted.

⚠️ #COVIDー19 | La prise d'anti-inflammatoires (ibuprofène, cortisone, ...) pourrait être un facteur d'aggravation de l'infection. En cas de fièvre, prenez du paracétamol.
Si vous êtes déjà sous anti-inflammatoires ou en cas de doute, demandez conseil à votre médecin.

-- Olivier Véran (@olivierveran) March 14, 2020

French heath officials also warned of using anti-inflammatories as they are known to pose a risk to people with infectious diseases because they tend to reduce the body's immune system response, according to The Guardian .

They rather recommend taking paracetamol because "it will reduce the fever without counterattacking the inflammation".

"Anti-inflammatory drugs increase the risk of complications when there is a fever or infection," warned Jean-Louis Montastruc, the head of pharmacology at Toulouse Hospital, according to The Guardian.

The French Health Ministry has reportedly been advising patients since mid-January to consult pharmacies when purchasing common pain relievers such as ibuprofen, paracetamol and aspirin, to be reminded of the risks.

France is one of the worst-affected countries in Europe, which has been declared a new virus hotspot after infections on the continent rose dramatically this month, while those in China have been reported to be leveling off.

On Saturday, French Prime Minister Edouard Philippe announced that the number of infection cases in France jumped 4,499, among which 154 are in critical condition, whereas the death toll had risen to 91 people.

Philippe has also announced that the country would shut most shops, restaurants and entertainment facilities beginning midnight on Saturday and people should stay home as long as possible as the spread of coronavirus accelerates.

As part of the country's response to the pandemic, a number of iconic monuments in Paris have been closed, including the Eiffel Tower, the Louvre Museum, the Versailles Palace, Louvre, Orsay Museum and Centre Pompidou.

[Mar 15, 2020] A Planet of Viruses Second Edition Zimmer, Carl 9780226294209 Amazon.com Books

Mar 15, 2020 | www.amazon.com

That same year, another scientists named Dana Willner led a virus-hunting expedition of her own. Instead of a cave, she dove into the human body. Willner had people cough up sputum into a cup, and out of that fluid she and her colleagues fished out frag- ments of DNA. They compared the DNA fragments to millions of sequences stored in online databases. Much of the DNA was hu- man, but many fragments came from viruses. Before Willner's ex- pedition, scientists had assumed the lungs of healthy people were sterile. Yet Willner discovered that, on average, people have 174 species of viruses in the lungs. Only 10 percent of the species Will- ner found bore any close kinship to any virus ever found before.

[Mar 14, 2020] The most primitive testing for coronavirus in an autopsy or living person is as easy as looking through a microscope and positively identifying the virus as they are present in large qualtities

Mar 14, 2020 | www.moonofalabama.org

Peter AU1 , Mar 14 2020 6:26 utc | 215

Siotu
Testing for coronavirus in an autopsy or living person is as easy as looking through a microscope and positively identifying the virus. Just a bit slow or labour-electron microscope intensive for wholesale testing of populations.

[Mar 13, 2020] Vaccine is on horizon

Mar 13, 2020 | www.unz.com

Oscar Peterson , says: Show Comment March 13, 2020 at 2:59 pm GMT

@another anon

I'd rather take my chances with the virus than consume an Israeli vaccine

Don't blame you at all, but you don't have to make that choice!

A Canadian company says that it has produced a COVID-19 vaccine just 20 days after receiving the coronavirus's genetic sequence, using a unique technology that they soon hope to submit for FDA approval.

Medicago CEO Bruce Clark said his company could produce as many as 10 million doses a month. If regulatory hurdles can be cleared, he said in a Thursday interview, the vaccine could start to become available in November 2021.

An Israeli research lab has also claimed to have created a vaccine. But Clark says his company's technique, which has already been proven effective in producing vaccines for seasonal flu, is more reliable and easier to scale.

"There are a couple of others who are claiming that they have -- well, we will call them vaccine[s]" for COVID-19, he said. "But they're different technologies. Some are RNA- or DNA-based vaccines that have not yet been proven in any indication yet, let alone this one. Hopefully, they'll be successful."

https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/163739/?oref=d-river

And it's all thanks to DoD:

In 2010, the Defense Advanced Research Projects Agency, or DARPA, put together a $100 million program dubbed Blue Angel to look into new forms of vaccine discovery and production. A big chunk of that money went to Medicago to build a facility in North Carolina, where they showed that they could find a vaccine in just 20 days, then rapidly scale up production.

But it won't be ready for actual people for 18 months.

[Mar 12, 2020] Turn Up the Humidity in Your House

Mar 12, 2020 | angrybearblog.com

run75441 | March 12, 2020 12:46 pm

Healthcare Hot Topics This is coming from MEDPAGE TODAY , "Track the U.S. COVID-19 Outbreak in Real Time," Comments Section (3 comments), March 11, 2020 with regard to COVID-19

"The mechanism of seasonal effect for seasonal respiratory virus spread is believed to be humidity, not temperature. In New York state which has 220 cases, fomites lose moisture where indoor humidity is low, allowing the lighter particles to stay longer in the aerosol. In Florida and Arizona, with 38 cases, fomites gain moisture and weight from the humid air and fall to the floor faster. Northern Italy, where people wear winter coats in the media reports has dry, heated indoor air, while Southern Italy has humid indoor air.

Humidifying indoor air in schools, stores, churches, etc. may reduce seasonal influenza, respiratory syncytial virus, coronoviruses which produce the common cold, rhinoviruses and Covid-19, Airports, airliners, airport shuttles should be the highest priority. The goal should be humidifying to the level seen in summer without transmitting Legionella."

"The Philippines, Indonesia, Malaysia, Australia, Hong Kong have warmer, more humid air and much less Covid-19. Southern Italy has warmer, more humid indoor air than Northern Italy where indoor air is dry. The photographs in the media from places with the highest rate of Covid-19 spread show people wearing winter jackets."

"In warm humid climates, fomites absorb water from indoor air and sink to the floor. There is a fine layer of dust everywhere indoors and viral particles attach to charged dust particles.

The mechanism for seasonal respiratory virus transmission is: fomite size in dry heated indoor air promotes viral spread. Larger fomites in humid air fall to the floor and react with charged dust particles."

fomite definition: objects or materials which are likely to carry infection, such as clothes, utensils, and furniture.

microbiology definition: A fomes (pronounced /ˈfoʊmiːz/) or fomite (/ˈfoʊmaɪt/) is any inanimate object that, when contaminated with or exposed to infectious agents (such as pathogenic bacteria, viruses or fungi), can transfer disease to a new host.

This would include counter tops, etc.

likbez , March 12, 2020 4:10 pm

I think incompetent politicians who want to be seen to be acting but do not implement the necessary for containing the epidemics steps or take them too late are more important danger in this coronavirus outbreak then the disease itself.

Humidity about 50% is a double edge sword: it greatly stimulates growth of various bacteria and fungus. And Legionnaires disease is more dangerous type of virus pneumonia than COVID-19.

Legionnaires' disease is the cause of an estimated 2–9% of pneumonia cases that are acquired outside of a hospital.[1] An estimated 8,000–18,000 cases a year in the United States require hospitalization

Respiratory-care devices such as humidifiers and nebulizers used with contaminated tap water may contain Legionella species, so using sterile water is very important.[29]

It is also not clear if 50% humidity is enough to adversely affect the coronavirus virus.

https://www.hvac.com/faq/recommended-humidity-level-home/

•Excess moisture promotes the growth and spread of mold, mildew, fungi, bacteria, and viruses. These contaminants diminish indoor air quality, causing illness, and can also cause damage to your home.

•When indoor humidity levels are too high, asthma and allergy sufferers may experience worse or more frequent symptoms.

•High humidity indoors causes the home to feel muggy. You may notice visible condensation on windows and walls.

At 80% or higher humility your sheets feel wet. This for example is the case in Dominican republic.

In general, this temperature guide will show you where to keep your indoor relative humidity levels to ensure comfort.

•Outdoor temperature over 50˚F, indoor humidity levels shouldn't exceed 50%

•Outdoor temperature over 20˚F, indoor humidity levels shouldn't exceed 40%

Over 50% humility can probably be maintained for prolong time only along with ultraviolet lamp disinfection of the room and daily change of bed sheets and weekly washing of pillows.

It is also not clear if the coronavirus can survive after drying of aerosol saliva particles that carry them. Probably not.

At the same time places with a very high humidity such as Hong Kong and Taiwan were less affected by the coronavirus.

[Mar 12, 2020] The NYT now has a section of free coronavirus coverage

The NYT now has a section of free coronavirus coverage, including our live briefing, maps of confirmed cases and advice on how to prepare for the outbreak
Quote: "If you begin to have a high fever, shortness of breath or any other more serious symptom, the best thing to do is to call your doctor to let them know and inquire about next steps. (Testing for coronavirus is inconsistent right now -- there are not enough testing kits, and it's dangerous for people with coronavirus to go into a doctor's office and risk infecting others. So please follow your doctor's instructions.) Check the C.D.C. website and your local health department for advice about how and where to be tested"
Mar 12, 2020 | www.nytimes.com

Latest Updates

Trump says domestic travel restrictions are a possibility. Days after being with Trump and Pence, Brazilian official tests positive for the virus, reports say. Europe condemns the U.S. travel ban as more nations add restrictions. Pence says to expect thousands of more cases in the U.S. California calls for a ban on large gatherings as states take measures to rein in the spread. Wall Street opens sharply lower after European markets tumble. A JetBlue passenger learns, in the air, that he has the virus. How to Prepare for the Coronavirus Keep your hands clean, and keep your distance from sick people Stay home if you are sick Unless you are already infected, face masks won't help Stock up on home supplies, medicine and resources Prepare your family, and communicate your plan With children, keep calm and carry on -- and get the flu shot Concerned about the stock market? Take a deep breath. Here's what you can do: Keep your hands clean, and keep your distance from sick people Stay home if you are sick Unless you are already infected, face masks won't help Stock up on home supplies, medicine and resources Prepare your family, and communicate your plan With children, keep calm and carry on -- and get the flu shot Concerned about the stock market? Take a deep breath.

[Mar 12, 2020] Korean model is that grocery are ordered (online or phone?) and delivered to the door, increasingly, people pick the grocery without physical contact with delivery people

Mar 12, 2020 | www.moonofalabama.org

Mina | Mar 11 2020 17:20 utc | 10

Sorry to say but... social distancing is one thing but how do you get some food? are you ready to wash up everything you bought at supermarket and change your clothes each time you go out and your bedsheets every morning?

Piotr Berman , Mar 11 2020 17:29 utc | 16

Korean model is that grocery are ordered (online or phone?) and delivered to the door, increasingly, people pick the grocery without physical contact with delivery people. Korean cities are quite dense from what I understand. Initially, shoppers abandoned big supermarket for neighborhood stores, neighborhood stores usually belong to big chains, like in Germany, so there are website for ordering groceries, but they are delivered over short distances.

Because having food delivered was already popular, a massive increase could be easy to handle. E.g. with more orders to the same address (high rise living is the norm), it takes less time for an individual delivery.

Piotr Berman , Mar 11 2020 17:37 utc | 20

I was thinking that "no contact shopping" in USA could be more practical with people arriving at their big supermarket (or local store in a rural area) and picking up pre-paid boxes (could be just open boxes that could be left empty).

[Mar 12, 2020] Seventy percent of US citizens have hypertension which is No.2 risk factor for COVID-19 (just after cadiovascular desease). Heavy smokers another important risk group

Mar 12, 2020 | www.moonofalabama.org

Joerg , Mar 11 2020 22:40 utc | 126

This was based on the virus' affinity for the ACE2 receptor in the lungs. It is also thought to have a higher prevalence in heavy smokers. Iran and Italy are countries where people smoke heavily. In Iran smoking related disease accounts for about 20% of fatalities in males.

Risk: Hypertension ( high blood pressure)

The graphs in my comment above (88) are from a German language article ( https://www.heise.de/newsticker/meldung/Zahlen-bitte-3-4-Coronavirus-Fallsterblichkeit-False-Number-4679338.html?seite=all ). There I read that 70 % of US citizens have hypertension while in Japan it's only 16 % and in China - of those who were confirmed Covid-19- patients - it's only 12.8 %.

I believe that it is lecithin (soy, fish) that East-Asians protect from hypertension.

As a heavy smoker I got a "smoker-leg" some years ago. I got successfully rid of it with lecithin, because I read that lecithin dissolves 'bad fats'. These 'bad fats' can't be put into the liver, because unlike 'good fats' they would destroy the liver. And thus our blood puts the 'bad fats' into the walls of our arteries, which then swell like balloons. Lecithin dissolves/cracks these 'bad fats' so that they now can be eliminated by the liver.

As not only smoking produces 'bad fats' (too long molecules?) lecithin in general will make the blood vessels fit again and by this certainly lower blood-pressure.

[Mar 11, 2020] Self-isolation is important for people most vulnerable for COVID-19

Notable quotes:
"... I have no illusion this behavior will guarantee anything, but que faire? ..."
Mar 11, 2020 | www.nakedcapitalism.com

Brooklin Bridge , March 11, 2020 at 11:49 am

I just got a call yesterday from close friends who must still think this is a joke and they wanted me to come out to a restaurant with them in about a weeks time. Six weeks ago, I would have gone.

I just told them the truth, thanking them very much for being so thoughtful, and also suggesting that this was more serious than people might realize, but I didn't go into too much detail as I've learned it's counter productive. I did, however, point out that due to our for profit health care system, we will get a much greater and faster spread of covid-19 due to prohibitive costs of any health care visit.

Couldn't resist that one; talk about res ipsa loquitur.

For a couple of weeks now, I have been quite up front with close friends, slightly less so with others, but refuse to go out unless I have to and can somewhat control how many people will be around (as in going to the super market very early am during the week).

I have no illusion this behavior will guarantee anything, but que faire?

[Mar 11, 2020] By e-mail, from National Nurses United:

Mar 11, 2020 | www.nakedcapitalism.com

Registered nurses are outraged to learn that the Centers for Disease Control (CDC) on Tuesday further weakened its guidance on measures to contain COVID-19. These changes include, among other things, rolling back personal protective equipment (PPE) standards from N-95 respirators to allow simple surgical masks; not requiring suspected or confirmed COVID-19 patients to be placed in negative pressure isolation rooms at all times; and weakening protections for health care workers collecting diagnostic respiratory specimens. These are moves that National Nurses United nurses say will gravely endanger nurses, health care workers, patients, and our communities

"If nurses and health care workers aren't protected, that means patients and the public are not protected," said Bonnie Castillo, RN and CNA/NNOC and NNU executive director. "This is a major public health crisis of unknown proportions. Now is not the time to be weakening our standards and protections, or cutting corners. Now is the time we should be stepping up our efforts."..

In addition to lobbying almost every federal health agency, the presidential administration, and members of Congress, and California health agencies to step up protections, NNU recently surveyed RNs nationwide, finding that the vast majority of the nation's health care facilities are unprepared for COVID-19, with only 29 percent of nurses reporting that their hospitals have a plan in place to isolate a coronavirus patient, and only 30 percent saying their employer has enough personal protective equipment if there is a rapid surge in patients with possible COVID-19 infections.

Many hospitals and healthcare facilities have failed to provide adequate personal protective equipment to nurses working with COVID-19 patients. Some facilities are telling nurses to continue to work while asymptomatic, even though they've been exposed to the virus and might be contagious. Testing at hospitals has been sporadic.

[Mar 11, 2020] Avoidance of couded places is now of paramount importance. Specialists suggested ramping up alternatives to face-to-face visits, tetemedicine, "car visits", telephone consultation hotlines.

Mar 11, 2020 | www.nakedcapitalism.com

Expat2uruguay , , March 11, 2020 at 6:31 am

I found this very interesting personal report on flutrackers:

Something else to share, here (reproduced exactly as I received it):

3/8/2020

Notes from the front lines:

I attended the Infectious Disease Association of California (IDAC) Northern California Winter Symposium on Saturday 3/7. In attendance were physicians from Santa Clara, San Francisco and Orange Counties who had all seen and cared for COVID-19 patients, both returning travelers and community-acquired cases. Also present was the Chief of ID for Providence hospitals, who has 2 affected Seattle hospitals under his jurisdiction. Erin Epson, CDPH director of Hospital Acquired Infections, was also there to give updates on how CDPH and CDC are handling exposed health care workers, among other things. Below are some of the key take-aways from their experiences.

1. The most common presentation was one week prodrome of myaglias, malaise, cough, low grade fevers gradually leading to more severe trouble breathing in the second week of illness. It is an average of 8 days to development of dyspnea and average 9 days to onset of pneumonia/pneumonitis. It is not like Influenza, which has a classically sudden onset. Fever was not very prominent in several cases. The most consistently present lab finding was lymphopenia (with either leukocytosis or leukopenia). The most consistent radiographic finding was bilateral interstitial/ground glass infiltrates. Aside from that, the other markers (CRP, PCT) were not as consistent.

2. Co-infection rate with other respiratory viruses like Influenza or RSV is 24 hours apart.

... ... ...

10. All suggested ramping up alternatives to face-to-face visits, tetemedicine, "car visits", telephone consultation hotlines.

11. Sutter and other larger hospital systems are using a variety of alternative respiratory triage at the Emergency Departments.

12. Health Departments (CDPH and OCHD) state the Airborne Infection Isolation Room (AIIR) is the least important of all the suggested measures to reduce exposure. Contact and droplet isolation in a regular room is likely to be just as effective. One heavily affected hospital in San Jose area is placing all "undifferentiated pneumonia" patients not meeting criteria for COVID testing in contact+droplet isolation for 2-3 days while seeing how they respond to empiric treatment and awaiting additional results.

Feel free to share. All PUIs in Monterey Country so far have been negative.

Martha.

Martha L. Blum, MD, PhD

Ignacio , March 11, 2020 at 6:52 am

Consequences of widespread denialism. At home, the virologist was not taken seriously until last Monday. I advised my wife last week not to assist to some meeting in closed doors, my son not to go to a concert, a friend of mine not to travel to Switzerland. They finally conceded I was right this week. The runners chat was complaining about cancellation of events until yesterday and I have received in chats lots of hyperventilating noises. Not helpful. We are now in Madrid replicating quite exactly events occurring in Italy 7-10 days before. Expect the same elsewhere.

Wukchumni , March 11, 2020 at 7:27 am

I’d mentioned yesterday that a group of 14 people from LA had all contracted Covid-19 @ an Italian ski resort, and 3 are very ill.

https://www.dailymail.co.uk/news/article-8094515/Doctor-treating-coronavirus-patients-LA-suburb-calls-schools-shut-immediately.html

I’m thinking of making up some lame excuse to not go skiing next week, a phantom injury or some other malady of my imagination.

Why not just admit to my friends that i’m afraid of mixing with a large group of people, especially so @ lunch, where we are in close proximity to a lot of other folks all milling around?

We are still in heavy denial-myself included, in that I feel my friends will think less of me if I was to give them the real reason, in that I don’t want to die, just yet.

An e-mail to my family regarding how bad the crisis is and will be here soon, was similar to my frantic e-mails & calls in the summer of 2008 regarding how shaky things are financially on Wall*Street, please be ready! They did nothing.

When I related that ‘Dr Drew’ (a sister sent me a video of his-after I sent out the Bergamo doctor’s account) who claimed Covid-19 was a press engineered fantasy, was just an addiction specialist and judging from where he hangs his hat (Breitbart, Washington Examiner, erc) everything he does is politically motivated hard right, one of my sisters asked me not to politicize the matter.

Being a Cassandra ain’t all that.

vlade , March 11, 2020 at 8:30 am

We took our daughter from school even before they closed them, because we suspected (rightly, as it turned out), that some parents coming from midterm sky trips to Italy will ignore the quarantine.

A friend of mine sent half of his staff WFH, and some of his business contacts see him as mad now.

That said, majority of people here support the drastic reaction, and would be happy to support even more dramatic ones. For example, a CEO of a major movie theater chain got quite a bit of kudos today when he said that while they could keep smaller theatres open, he doesn’t see how it’s better to keep 50 people bunched together than 100, so they close it all until further notice.

Wukchumni , March 11, 2020 at 2:34 pm

This sums it up for me…

You might have fears today: What if I overreact? Will people laugh at me? Will they be angry at me? Will I look stupid? Won’t it be better to wait for others to take steps first? Will I hurt the economy too much?

But in 2–4 weeks, when the entire world is in lockdown, when the few precious days of social distancing you will have enabled will have saved lives, people won’t criticize you anymore: They will thank you for making the right decision.

https://medium.com/@tomaspueyo/coronavirus-act-today-or-people-will-die-f4d3d9cd99ca

rtah100 , March 11, 2020 at 3:37 pm

(from the little book of VC aphorisms):
– Nobody thanks you for being right.

[Mar 11, 2020] China approves Favilavir as first antiviral drug against ...

Mar 11, 2020 | vuuzletvph.com

Your browser indicates if you've visited this link https://vuuzletvph.com /favilavir-first-covid-19-drug-approved/ The government of Taizhou in Zhejiang province declared Sunday that Favilavir, formerly known as Fapilavir, an antiviral that has shown efficacy in the treatment of the novel coronavirus (), has been approved to be sold in the market.It is the first antiviral drug approved by the National Medical Products Administration for marketing since the outbreak happened.

[Mar 11, 2020] Does the sun kill the new coronavirus Expert explains

Mar 11, 2020 | cntechpost.com

Special Report: Fighting The New Coronavirus

Can the virus freeze to death at low temperatures? Will it disappear as the temperature rises? With the outbreak of a new coronavirus in Wuhan and across China, there have been more and more recent statements about the virus and temperature.

These judgments lead to different conclusions no matter true or false, but they are widely circulating.

Does the sun kill the new coronavirus? Expert explains-cnTechPost <img alt="Does the sun kill the new coronavirus? Expert explains-cnTechPost" src="https://img.cntechpost.com/images/2020/01/28/071.jpg" />

How resistant is the new coronavirus to temperature? Is it suitable for outdoor activities after fine weather? Ma Ke, deputy chief physician of the Department of Infectious Diseases of Tongji Hospital, answers these questions.

1. Is the new coronavirus more afraid of heat or cold?

Coronavirus is more sensitive to heat.

The virus is moderately stable in a suitable maintenance solution at 4 °C and can be stored for several years at -60 ° C.

However, as the temperature increases, the virus's resistance decreases, but it must reach a certain temperature for a certain time to inactivate the virus.

2. Does the ambient temperature affect the infectivity of the virus? Is there a difference in transmission in different regions (such as Northeast and Hainan)? Will the infectivity of the virus decrease as the temperature rises?

It can survive in different body fluids and even the surface of the object at room temperature for 2-10 days. Temperature mainly affects the survival time of the virus and does not affect its infectious capacity.

Because coronaviruses can be transmitted through respiratory aerosols, inactivating the virus in various ways and adopting multifaceted protective measures can minimize the possibility of infection.

3. How much and how long does the high temperature have a killing effect on the virus? High-temperature environment disinfection? Does turning on air conditioning and heating work?

The virus is sensitive to heat and can effectively inactivate the virus when it reaches a temperature of 56 ° C for 30 minutes. However, it is impossible to achieve the effect of inactivating the virus by raising the ambient temperature by heating with an air conditioner, and the effect of the virus cannot be achieved by heating the temperature.

4. In addition to fear of heat, what is the virus afraid of? (Disinfectant, ethanol, chlorine-containing disinfectant, etc., correct use)

In addition to killing the virus at high temperatures, lipid solvents such as ether, 75% ethanol, chlorine-containing disinfectants, peracetic acid, and chloroform can effectively inactivate the virus.

Air disinfection method:

1. Some people open the window twice a day for 30 minutes each time.

2. When there is an ultraviolet lamp, irradiate the ultraviolet lamp once a day in an unmanned room for more than 1 hour each time.

3. Disinfection method for the surface and ground of environmental objects: use 1000mg / L chlorine-containing disinfectant or peroxyacetic acid and hydrogen peroxide paper towels to wipe and disinfect thoroughly, twice a day.

Experts remind:

First, the sun's irradiation temperature cannot reach 56 degrees, and the intensity of ultraviolet rays in sunlight can not reach the intensity of ultraviolet lamps.

Second, it needs a duration of 56 degrees and 30 minutes, and the ultraviolet lamp is irradiated for 60 minutes. The conditions must be met at the same time, which is difficult to achieve in the ordinary outside environment.

[Mar 11, 2020] Corona Virus COVID-19 Experienced doctor's opinion

He correctly stated "Hysteria is going out the roof"
Mar 04, 2020 | www.youtube.com

Older doctor's assessment of the new Coronavirus. His many years of experience and his opinion of this new "chest flu". They talk about the terrible flu of 1918 when 50 million died.

We have had just as bad "pandemics" since then but we now have antibiotics for the bacterial pneumonia and better hospital care. Few people went into hospitals back then.

The first president to be born in a hospital was Jimmy Carter. Many people still die from world wide infections (called pandemics). HIV and HPV are pandemics also.

[Mar 11, 2020] Coronavirus (COVID-19) What People With Asthma Need to Know

Mar 11, 2020 | community.aafa.org

The CDC has also released new guidelines for people who are at high risk, which includes people with asthma. They recommend people at high risk:

If there is an outbreak in your local community, they also recommend you stay home as much as possible.

With this update, we have also added more questions and answers below from Dr. Mitchell Grayson from AAFA's Medical Scientific Council.

The new coronavirus is estimated to spread at a similar rate to the flu. It is important to take steps to prevent getting sick, like frequent hand-washing and avoiding people who are sick.

In the U.S., flu activity is still high. According to CDC estimates, the flu may have infected as many as 49 million people this season, and as many as 52,000 may have died. If you get sick, it is more likely it is the flu unless you live in an coronavirus outbreak area.

Note: Because this is a constantly changing situation, this data may not represent the most up-to-date numbers as state health departments and the CDC independently confirm infections and deaths. We will update this blog when possible.


The 2019 new coronavirus (also known as COVID-19 or 2019-nCoV) is a hot topic in the news. Now that it has spread to the U.S., you may wonder if you should be concerned. It is a respiratory virus , meaning it affects the lungs, so what do people with asthma need to know?

COVID-19 Cases in the U.S. (according to the CDC as of 3/10/2020)
Travel-related (confirmed) 83
Person-to-person spread (confirmed) 36
Being investigated 528
Total cases 647
What Is Coronavirus (COVID-19)?

A coronavirus is a type of virus that often occurs in animals. Sometimes, it can spread to humans. This is rare.

In December 2019, a new coronavirus started spreading. Experts think people first caught the virus at a fish and live animal market. Now it is spreading from person to person.

According to the Centers for Disease Control and Prevention (CDC), coronavirus symptoms can include:

The CDC believes symptoms may appear two to 14 days after coming in contact with the virus.

As of March 10, 2020, there are more than 113,851 cases of COVID-19 in the world. The World Health Organization (WHO) has declared it a global health emergency.

How Is It Spread?

The virus is spread through coughing and sneezing. The virus will be in droplets that are coughed or sneezed out into the air. These are heavy droplets and they quickly fall to the ground/surface below.

People who are within 1 to 2 meters (3 to 6 feet) of someone who is ill with coronavirus may be within the zone that droplets can reach. If someone who is sick coughs or sneezes on your face, you may get infected. This is why it is recommended that people who are sick should cough/sneeze into their elbows or a tissue and throw it away and wash their hands. People who are sick should also wear a mask to help stop the spread of illness.

The coronavirus may also live on surfaces that people have coughed and sneezed on. If you touch a surface with the virus on it and then touch your mouth, nose or eyes, you may get sick.

Who Is at Risk From the Coronavirus?

Most Americans are still at a low risk of getting coronavirus, says the CDC.

At this time, little is known about how the coronavirus affects people with asthma . One study of 140 cases showed no link to asthma. 1 According to the WHO and the CDC, the highest risk groups include:

People with asthma should take precautions when any type of respiratory illness is spreading in their community.

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